Results 181 to 190 of about 1,937,419 (235)

Comprehensive evaluation of AlphaFold/OpenFold prediction of experimentally unresolved proteins through novel metrics. [PDF]

Brief Bioinform
Díaz FR, Orschanski D, Folco JI, Ceci JE, Nibeyro G, Robles Vega H, Nicola JP, Fernández EA.   +7 more
europepmc   +1 more source

Integrating Genetic Modifier Genotype With Serum Proteomics in Duchenne Muscular Dystrophy Clinical Trials Links LTBP4 Genetic Modifier to IL‐23/CD93 Pathways in Muscle

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic modifiers of Duchenne muscular dystrophy (DMD) that alter disease severity or response to therapy have been reported using natural history or registry data sets of older corticosteroid‐treated patients. We tested associations of genetic modifiers on motor function outcomes in young (4 to < 7 years) steroid naïve clinical trial ...
Utkarsh J. Dang, Yuan Fang, Daniele Sabbatini, Elena Pegoraro, Luca Bello, Paula R. Clemens, Michela Guglieri, John van den Anker, Jesse Damsker, Laura Hagerty, Yetrib Hathout, Michael Ziemba, Lauren Morgenroth, Surajit Bhattacharya, Kanneboyina Nagaraju, Jyoti K. Jaiswal, Eric P. Hoffman   +16 more
wiley   +1 more source

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

Volumetric analysis of root coverage with porcine acellular dermal matrix: Case study. [PDF]

Clin Adv Periodontics
Vargas-Quiroga ED, da Silva GFF, Tonin BSH, Novaes-Jr AB, Reis MBL.   +4 more
europepmc   +1 more source

Deep learning-based identification, classification and segmentation of infraosseous periodontal defects using a YOLOv8 neural network. [PDF]

BMC Oral Health
Gu X, Orosz P, Somodi K, Li X, Yang L, Yang H, Ramseier C, Palkovics D.   +7 more
europepmc   +1 more source

Novel DMD Frameshift Variant (p.Leu2017Profs*5) in Spectrin-Like Repeat 16 Expands the Mutational Spectrum of DMD. [PDF]

Mol Genet Genomic Med
Lin YC, Luxton GWG, Lee HJ, Lu YY, Yang HC, Hung KS, Lai MT, Hu CF.   +7 more
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Influence of acellular dermal matrix on peri-implant soft tissue phenotype and marginal bone loss following immediate implant placement in the anterior maxilla: a randomized controlled clinical trial. [PDF]

BMC Oral Health
Haggag MA, Alrawooji MF, Attia AMM.
europepmc   +1 more source

Effects of a Xenogeneic Bone Graft Combined with Platelet-Rich Fibrin Obtained Using Two Distinct Centrifugation Protocols on Critical-Size Rat Calvarial Defects: A Microtomographic, Histomorphometric, and Confocal Laser Scanning Microscopy Analysis. [PDF]

J Funct Biomater
Martins UDCC, Sávio DSF, Okamoto R, Mourão CF, Miron RJ, de Souza SLS, Furlaneto FAC, Messora MR.   +7 more
europepmc   +1 more source