Results 51 to 60 of about 33,340 (222)

IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections

Frontiers in Immunology, 2018
Influenza virus infections particularly when followed by bacterial superinfections (BSI) result in significant morbidities and mortalities especially during influenza pandemics.
Kelly M. Shepardson, Kyle Larson, Laura L. Johns, Kayla Stanek, Hanbyul Cho, Julia Wellham, Haley Henderson, Agnieszka Rynda-Apple   +7 more
doaj   +1 more source

Eicosanoid-Activated PPARα Inhibits NFκB-Dependent Bacterial Clearance During Post-Influenza Superinfection

Frontiers in Cellular and Infection Microbiology, 2022
Secondary bacterial infection (superinfection) post influenza is a serious clinical complication often leading to pneumonia and death. Eicosanoids are bioactive lipid mediators that play critical roles in the induction and resolution of inflammation ...
Ronald Lucarelli, Norma Gorrochotegui-Escalante, Jessica Taddeo, Bettina Buttaro, Bettina Buttaro, Joris Beld, Vincent Tam   +6 more
doaj   +1 more source

Systematic Review and Meta‐Analysis Suggested That Neutrophils Predominated the Airways of Children With the Respiratory Syncytial Virus

Acta Paediatrica, EarlyView.
ABSTRACT Aim The respiratory syncytial virus (RSV) is a predominant aetiology of early‐life respiratory infections. This systematic review and meta‐analysis compared the cell types involved in airways inflammation in children with and without RSV, noting that immune responses can influence long‐term complications and may involve different inflammatory ...
Muhammad Pradhika Mapindra, Naz Chughtai, Muhammad Pradhiki Mahindra, Paul McNamara, Cissy Kartasasmita, Malcolm Gracie Semple, Mahendra Tri Arif Sampurna, Howard Clark, Jens Madsen   +8 more
wiley   +1 more source

Carriage of the Laboratory of Genetics and Physiology Protein 2 Q425R Variant Reduces Liver Disease Severity in European Patients With Chronic Hepatitis Delta

Alimentary Pharmacology &Therapeutics, EarlyView.
In patients with chronic hepatitis Delta, the LGP2 Q425R variant (rs2074158 CC/CT genotypes), associated with an enhanced interferon response in vitro, becomes progressively less frequent as liver disease advances from no cirrhosis to cirrhosis, and to cirrhosis with progressive increase of portal hypertension evaluated by thrombocytopenia.
Sara Cmet, Elisabetta Degasperi, Annarosa Cussigh, Elisabetta Fontanini, Maria Paola Anolli, Floriana Facchetti, Riccardo Perbellini, Dana Sambarino, Sara Uceda Renteria, Mariapaola Callegaro, Davide Bitetto, Elisa Fumolo, Ezio Fornasiere, Elena Garlatti Costa, Edmondo Falleti, Pietro Lampertico, Pierluigi Toniutto   +16 more
wiley   +1 more source

Unusual SARS-CoV-2 intra-host diversity reveals lineages superinfection

, 2021
Supplementary material of the paper "Unusual SARS-CoV-2 intra-host diversity reveals lineages superinfection"
Gabriel Wallau (4662724), Filipe Zimmer Dezordi (8097014)   +1 more
core   +1 more source

Infection kinetics and antibody responses in Deccani sheep during experimental infection and superinfection with bluetongue virus serotypes 4 and 16 [PDF]

Veterinary World, 2019
Aim: The current study was designed to understand the infection kinetics and antibody responses of major circulating serotypes of bluetongue virus (BTV) in India, i.e., BTV-4 and BTV-16 through experimental infection and superinfection of Deccani sheep ...
Kalyani Putty, Abdul Muzeer Shaik, Shaik Jahangeer Peera, Y. Narasimha Reddy, P. P. Rao, Sunil R. Patil, M. Shreekanth Reddy, B. Susmitha, J. Shiva Jyothi   +8 more
doaj   +1 more source

Superinfection rate among the patients treated with carbapenem versus piperacillin/tazobactam: Retrospective observational study

Journal of Infection and Public Health, 2021
Background: Superinfection is a new isolate pathogen after 48 h of antibiotic treatment or within one week of treatment discontinuation. In many studies carbapenem and piperacillin–tazobactam were associated with high risk of superinfection.
Hessa Al Muqati, Abdulrahman Al Turaiki, Fahad Al Dhahri, Huda Al Enazi, Abdullah Althemery   +4 more
doaj   +1 more source

The Psoriasis–Eczema Interface: Clinical Classification and Therapeutic Implications From a Bicentric Experience

International Journal of Dermatology, EarlyView.
The psoriasis–atopic dermatitis interface: four clinical phenotypes (coexisting, overlapping, biologic‐induced eczema, dupilumab‐induced psoriasis) across 105 patients from two Italian tertiary centers. JAK inhibitors achieved the highest response rates across all phenotypes, reflecting their mechanistic rationale targeting shared JAK‐STAT downstream ...
Michela D'Agostino, Gennaro Marco Falco, Eleonora De Luca, Clara De Simone, Alessandro Di Stefani, Maddalena Napolitano, Ketty Peris, Matteo Megna, Giacomo Caldarola   +8 more
wiley   +1 more source

Characterization of inflammatory mediators in COVID-19 plasma and its association with bacterial superinfection.

, 2022
(A) PCA of healthy donors (white, n = 17), acute- (red, n = 25) and rec- (blue, n = 19) phase COVID-19 patients grouping the plasma cytokine levels and status of secondary bacterial infections (superinfection).
Tiziano A. Schweizer (8201919), Sanne Hertegonne (11927244), Pedro D. Wendel Garcia (10169740), Reto A. Schuepbach (10874816), Alejandro Gómez-Mejia (7054121), Claudio Acevedo (11927232), Elena Parietti (11927247), Clément Vulin (11927238), Daniel A. Hofmaenner (11405300), Markus Huemer (3098184), Chun-Chi Chang (3477179), Judith Bergada-Pijuan (11927235), Srikanth Mairpady Shambat (9045473), Nataliya Miroshnikova (6795359), Annelies S. Zinkernagel (9045479), Matthias P. Hilty (9221972), Thomas C. Scheier (11927241), Silvio D. Brugger (6855176), Philipp Karl Buehler (10946649)   +18 more
core   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source