Results 81 to 90 of about 45,804 (257)
npj Vaccines, 2020 A majority of the world’s population is infected with HSV-1, highlighting the need for vaccines that are effective in HSV-1-seropositive hosts. We established a superinfection model by infecting mice intranasally with a sublethal dose of HSV-1, which ...
Clare Burn Aschner, D. Knipe, B. Herold
semanticscholar +1 more source
Dupilumab in Paediatric Netherton Syndrome: Two Case Reports and a Review of the Literature
Australasian Journal of Dermatology, EarlyView.ABSTRACT Netherton Syndrome (NS) is a rare genodermatosis characterised by a triad of ichthyosiform erythroderma, an atopic diathesis, and trichorrhexis invaginata, for which no effective management is currently approved in Australia. Dupilumab has demonstrated considerable effectiveness in the treatment of atopic conditions in the paediatric ...
Jacqueline Tu +5 more
wiley +1 more source
Structural basis of superinfection exclusion by bacteriophage T4 Spackle
Communications Biology, 2020 A bacterial cell infected with T4 phage rapidly establishes resistance against further infections by the same or closely related T-even-type bacteriophages – a phenomenon called superinfection exclusion.
K. Shi +5 more
semanticscholar +1 more source
Acta Paediatrica, EarlyView.ABSTRACT Aim The respiratory syncytial virus (RSV) is a predominant aetiology of early‐life respiratory infections. This systematic review and meta‐analysis compared the cell types involved in airways inflammation in children with and without RSV, noting that immune responses can influence long‐term complications and may involve different inflammatory ...
Muhammad Pradhika Mapindra +8 more
wiley +1 more source
Examining neutralizing antibody activity as an immune correlate of HIV-1 superinfection [PDF]
, 2015 Thesis (Master's)--University of Washington, 2015Background: HIV-1 superinfection occurs roughly half as frequently as initial infection, suggesting the HIV-1 immune response is partially protective of reinfection.
Dingens, Adam Spier
core
Microorganisms, 2021 Background: The role of bacterial co-infection and superinfection among critically ill COVID-19 patients remains unclear. The aim of this study was to assess the rates and characteristics of pulmonary infections, and associated outcomes of ventilated ...
Regev Cohen +9 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Superinfection with bacteria, such as Staphylococcus aureus, following influenza leads to increased morbidity and mortality compared to infection with either the bacteria or the virus alone.
V. Tam +10 more
semanticscholar +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.In patients with chronic hepatitis Delta, the LGP2 Q425R variant (rs2074158 CC/CT genotypes), associated with an enhanced interferon response in vitro, becomes progressively less frequent as liver disease advances from no cirrhosis to cirrhosis, and to cirrhosis with progressive increase of portal hypertension evaluated by thrombocytopenia.
Sara Cmet +16 more
wiley +1 more source
Model-based estimation of superinfection prevalence from limited datasets
, 2018 Humans can be infected sequentially by different strains of the same virus. Estimating the prevalence of so-called ‘superinfection’ for a particular pathogen is vital because superinfection implies a failure of immunologic memory against a given virus ...
Joshua T. Schiffer +4 more
core +1 more source
, 2022 (A) PCA of healthy donors (white, n = 17), acute- (red, n = 25) and rec- (blue, n = 19) phase COVID-19 patients grouping the plasma cytokine levels and status of secondary bacterial infections (superinfection).
Tiziano A. Schweizer (8201919) +18 more
core +1 more source