Results 131 to 140 of about 163,323 (377)

Superior vena cava syndrome [PDF]

open access: yesQJM: An International Journal of Medicine, 2019
K Horiuchi   +3 more
openaire   +4 more sources

Effects of Shunt Position on the Prognosis of Transjugular Intrahepatic Portosystemic Shunt in Patients With Cirrhotic Esophagogastric Variceal Bleeding

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
The challenge of transjugular intrahepatic portosystemic shunt (TIPS) remains the puncture of the portal vein. Establishing an optimal shunt position in the left branch of the portal vein would be a better option for reducing the risk of postoperative hepatic encephalopathy and stent dysfunction.
Yi‐Han Yang   +6 more
wiley   +1 more source

Targeted Delivery of miR‐34a via Anti‐CD47 Antibody Conjugates for Enhanced Cancer Immunotherapy in Triple Negative Breast Cancer

open access: yesSmall, EarlyView.
aCD47‐C‐miR34a, an antibody‐oligonucleotide platform combining an anti‐CD47 antibody with miR‐34a, is designed for targeted therapy in TNBC. This approach improved delivery and restored the tumor‐suppressing function of miR‐34a, enhanced CD8+ T‐cell activation, and inhibited tumor growth, providing a potential strategy to overcome immune evasion and ...
Youngri Ryu   +11 more
wiley   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

open access: yesSmall Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai   +9 more
wiley   +1 more source

Characterizing fetoplacental response to acute maternal hyperoxygenation in suspected coarctation of aorta using fetal cardiac MRI

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To characterize the fetoplacental response to acute maternal hyperoxygenation (AMH) in fetuses with suspected coarctation of the aorta (CoA) using fetal cardiac magnetic resonance imaging (MRI). Methods Pregnant women carrying a fetus with suspected CoA were recruited prospectively from a tertiary fetal cardiology center as part of ...
M. P. M. van Poppel   +10 more
wiley   +1 more source

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