Results 41 to 50 of about 33,770 (311)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Images in Medicine Representing the Management of Mesiodens in Different Dentitions [PDF]
Journal of Clinical and Diagnostic ResearchMesiodens are the most common type of supernumerary teeth, typically located between the two maxillary central incisors [1]. Hereby, three cases of mesiodens in primary, mixed and permanent dentition are presented, along with a discussion of how the ...
Simron Baishya +3 more
doaj +1 more source
Functional Reorganization After Four-Week Brain–Computer Interface-Controlled Supernumerary Robotic Finger Training: A Pilot Study of Longitudinal Resting-State fMRI [PDF]
, 2022 Yuan Liu +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Supernumerary horseshoe kidneys [PDF]
The British Journal of Radiology, 2015 To the Editor, We read an excellent pictorial review on horseshoe kidneys by Schiappacasse et al1 in the January 2015 issue of the BJR. We would like to supplement to the list a rare but interesting congenital anomaly associated with horseshoe kidneys.
B, Sureka, K, Bansal, A, Arora
openaire +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2014 Background: Supernumerary teeth are one of the most widely reported and significant anomaly in patients affecting the primary and early mixed dentition.
Rajesh T Anegundi +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
SRM Journal of Research in Dental Sciences, 2016 Supernumerary teeth are present in addition to the normal complement of teeth in permanent or deciduous dentitions. Incidence is high in a permanent dentition, affecting both the gender. They are more common in males, with the male to female ratio of 2:1.
Pravesh Kumar Jhingta +5 more
doaj +1 more source