Results 61 to 70 of about 74,686 (398)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Güneydoğu Anadolu Bölgesi’nde dental anomalilerin görülme sıklığı

open access: yesSelcuk Dental Journal, 2018
Amaç: Bu çalışmanın amacı, Güneydoğu Anadolu Bölgesinde yaşayan bireylerde dental anomalilerin görülme sıklığının ve cinsiyetler arasındaki dental anomali görülme yatkınlıkların değerlendirilmesidir.Gereç ve Yöntemler: Çalışma Adıyaman Üniversitesi ...
Mahmut Koparal   +5 more
doaj   +1 more source

Reversion scheme for droplet parameters with rainbow refractometry based on Debye theory [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011)   +4 more
core  

Two new charismatic Pristimantis species (Anura: Craugastoridae) from the tepuis of “The Lost World” (Pantepui region, South America) [PDF]

open access: yes, 2013
Two new colourful species of direct-developing frogs of the genus Pristimantis are described from the summit of two isolated tepuis (sandstone table mountains) in the Eastern Pantepui District of the Guiana Shield highlands. Pristimantis jamescameroni sp.
Kok, Philippe J. R.
core   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Multiple maxillary and mandibular supernumerary teeth in twins: 5-year follow-up

open access: yesJournal of Dental Sciences, 2014
This is a case report of multiple supernumerary teeth of identical twins with 5 years of follow-up. The occurrence of supernumerary teeth in twins is an unusual event.
Jeng-Fen Liu, Hui-Ling Chen
doaj   +1 more source

A Case of Supernumerary Kidney [PDF]

open access: yesCureus, 2018
A supernumerary kidney is extremely rare, with less than 100 cases currently reported in the literature. When this variant is present, the additional renal parenchyma demonstrates its own collecting system, vascular supply, and distinct encapsulated parenchyma. Herein, we discuss the case of a supernumerary kidney in a 20-year-old male.
Joseph Limback   +3 more
openaire   +3 more sources

A Review of Supernumerary Teeth in the Premolar Region

open access: yesInternational Journal of Dentistry, 2018
Supernumerary teeth in the premolar region, unlike other supernumeraries, occur more often in the mandible where they are generally of the supplemental type.
K. Khalaf, Saaid Al Shehadat, C. Murray
semanticscholar   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

String theory and the Classical Stability of Plane Waves [PDF]

open access: yes, 2002
The presence of fields with negative mass-squared typically leads to some form of instability in standard field theories. The observation that, at least in the light-cone gauge, strings propagating in plane wave spacetimes can have worldsheet scalars ...
D. Amati   +52 more
core   +2 more sources

Home - About - Disclaimer - Privacy