Results 81 to 90 of about 74,686 (398)

Small supernumerary marker chromosomes: A legacy of trisomy rescue?

Human Mutation, 2018
We studied by a whole genomic approach and trios genotyping, 12 de novo, nonrecurrent small supernumerary marker chromosomes (sSMC), detected as mosaics during pre‐ or postnatal diagnosis and associated with increased maternal age.
N. Kurtas, L. Xumerle, L. Leonardelli, M. Delledonne, A. Brusco, K. Chrzanowska, A. Schinzel, D. Larizza, S. Guerneri, F. Natacci, M. Bonaglia, Paolo Reho, E. Manolakos, T. Mattina, F. Soli, Aldesia Provenzano, Ahmed Al-Rikabi, E. Errichiello, Lusine Nazaryan-Petersen, S. Giglio, N. Tommerup, T. Liehr, O. Zuffardi   +22 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Surgical Management of Impacted Supernumerary Tooth and Odontome under General Anesthesia in an Emotionally Immature Child: A Case Report

Indian Journal of Dental Sciences
The disorder known as hyperdontia is characterized by an excess of teeth or teeth that appear to be added to the normal amount of teeth. With a frequency ranging from 0.1% to 3.9% in permanent dentition and from 0.3% to 1.8% in deciduous dentition, it ...
Rasleen Dua, Pallavi Vashisth, N. Sathyajith Naik, Sriparna De   +3 more
doaj   +1 more source

Prevalence, characteristics, and morphology of supernumerary teeth among patients visiting a dental institution in Rajasthan

Contemporary Clinical Dentistry, 2018
Context: Supernumerary teeth/tooth (ST) is a developmental anomaly of dentition. Variation in developmental and eruption pattern of ST can lead to the development of numerous complications in oral cavity.
Pulkit Khandelwal, A Bhagavandas Rai, Bipin Bulgannawar, Neha Hajira, Abhijeet Masih, Arvind Jyani   +5 more
doaj   +1 more source

A CASE OF SUPERNUMERARY TOES. [PDF]

The Lancet, 1915
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openaire   +3 more sources

Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus

bioRxiv, 2018
Meiosis is a key cellular process of sexual reproduction involving the pairing of homologous sequences. In many species however, meiosis can also involve the segregation of supernumerary chromosomes, which can lack a homolog.
M. Habig, G. Kema, E. Stukenbrock
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Occurrence of bilaterally impacted mandibular supernumerary teeth: A rare case report and review of literature

SRM Journal of Research in Dental Sciences, 2016
Supernumerary teeth are present in addition to the normal complement of teeth in permanent or deciduous dentitions. Incidence is high in a permanent dentition, affecting both the gender. They are more common in males, with the male to female ratio of 2:1.
Pravesh Kumar Jhingta, Vinay Kumar Bhardwaj, Deepak Sharma, Nishant Negi, Sanjeev Vaid, Naresh Kumar   +5 more
doaj   +1 more source

Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes

bioRxiv, 2018
The presence of supernumerary centrosomes is prevalent in cancer, where they promote the formation of transient multipolar mitotic spindles. Active clustering of supernumerary centrosomes enables the formation of a functional bipolar spindle that is ...
Bernat Navarro-Serer, Eva Childers, Nicole M Hermance, Dayna L. Mercadante, Amity L Manning   +4 more
semanticscholar   +1 more source

3D MRI Tract‐Specific Spinal Cord Lesion Pattern Improves Prediction of Distinct Neurological Recovery

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To distinguish lateralized motor‐ and sensory‐tract damage after acute spinal cord injury (SCI) and explore its predictive power for motor and sensory recovery. Methods Thirty‐five SCI patients (two female) from a multi‐center data set (placebo‐arm of the Nogo‐A‐Inhibition in SCI trial) underwent routine T2‐weighted sagittal MRI ...
Lynn Farner, Tim M. Emmenegger, Simon Schading‐Sassenhausen, Julia Berroth, Maryam Seif, Armin Curt, Patrick Freund, The Nogo Inhibition in Spinal Cord Injury Study Group   +7 more
wiley   +1 more source