Results 31 to 40 of about 83,303 (314)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Optical probing of supersonic flows with statistical correlation [PDF]
, 1971 Remote sensing tool reliably measures statistical properties of supersonic turbulence. Tool neither affects nor is adversely affected by flow field.
Funk, B. H.
core +1 more source
Supersonic flow onto a solid wedge [PDF]
, 2007 We consider the problem of 2D supersonic flow onto a solid wedge, or equivalently in a concave corner formed by two solid walls. For mild corners, there are two possible steady state solutions, one with a strong and one with a weak shock emanating from ...
Chen +29 more
core +1 more source
Instability of supersonic compression ramp flow [PDF]
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2014 The instability of supersonic compression ramp flow is investigated. It is assumed that the Reynolds number is large and that the governing equations are the unsteady triple-deck equations. The mean flow is first calculated by solving the steady equations for various scaled ramp angles α , and the numerical results ...
Logue, R.P. +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Airfoil leading edge blowing to control bow shock waves
Scientific Reports, 2020 This manuscript presents a detailed characterization of active control of bow shock waves via leading edge injection, including subsonic coolant ejection and the appearance of Coanda effects.
Francisco Lozano, Guillermo Paniagua
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Vietnam Journal of Mechanics, 2007 Transonic flows are complex problems. At certain Mach numbers, in gas flows there are local transitions from the subsonic into the supersonic and reciprocally, especially the discontinuity throughout shock waves.
Hoang Thi Bich Ngoc
doaj +1 more source
Conditions for one-dimensional supersonic flow of quantum gases
, 2004 One can use transsonic Bose-Einstein condensates of alkali atoms to establish the laboratory analog of the event horizon and to measure the acoustic version of Hawking radiation. We determine the conditions for supersonic flow and the Hawking temperature
C. Farrell +8 more
core +2 more sources