Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Numerical and Experimental Modelling of Transition in a Separated Boundary Layer on the NACA63A421 Airfoil [PDF]
The article deals with design and numerical calculation of a variable test section for small supersonic wind tunnel. The supersonic wind tunnel is designed to be driven by a supersonic ejector.
Miroslav ĎURIŠ +3 more
doaj
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
An Analytical and Computational Investigation of Shock-Induced Vortical Flows with Applications to Supersonic Combustion [PDF]
The motivation for study of shock-induced vortical flows is the problem of achieving rapid and efficient mixing of fuel and oxidizer in a SCRAMJET engine.
Yang, Joseph
core +1 more source
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
Gas-Dynamic Temperature Stratification in the Leontiev Tube: Analytical Study and Numerical Modeling
Objective. The article is dedicated to the study of heat transfer processes in a Leontiev tube based on the principle of gas-dynamic temperature stratification.
R. S. Rudnik +2 more
doaj +1 more source
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
Numerical Study of Supersonic Cavity Flows with Different Turbulent Models
A numerical study of supersonic cavity flows is conducted with different turbulent models, including RANS, LES, DES, DDES, and IDDES. Firstly, a supersonic cavity-ramp flow with Ma∞ = 2.92 is simulated numerically.
Hongpeng Liu +3 more
doaj +1 more source
Numerical simulation of gap effect in supersonic flows
The gap effect is a key factor in the design of the heat sealing in supersonic vehicles subjected to an aerodynamic heat load. Built on S-A turbulence model and Roe discrete format, the aerodynamic environment around a gap on the surface of a supersonic ...
Song Mo +4 more
doaj +1 more source

