Results 31 to 40 of about 2,028,040 (187)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Desarrollo de la expresión oral como habilidad comunicativa y profesional pedagógica
Propuestas Educativas, 2020 El propósito de la presente investigación fue proponer tareas para que el futuro educador desarrolle la expresión oral, específicamente cuando cursa el básico curricular Teoría y Práctica de la Comunicación y el Lenguaje en el Programa Nacional de ...
Celeste del Valle Castillo Figuero
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Characterization and typology of goat production systems in the Southern Highlands of Peru [PDF]
Veterinary WorldBackground and Aim: Characterizing local animal production systems is crucial for sustainable livestock development. This study aimed to characterize the diversity of goat production systems in the Highlands of Chincha province, Ica, Peru.
Emmanuel Alexander Sessarego +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Geocarto InternationalSoil is a vital nonrenewable resource characterized by rapid degradation and slow regeneration processes. In this study, soil degradation in Jaén and San Ignacio was assessed via a multicriteria evaluation approach combined with remote sensing (RS) data.
Marielita Arce-Inga +9 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source