Results 71 to 80 of about 2,296,173 (238)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Nuevas tecnologías e inclusión en el ámbito de la Educación Social [PDF]
, 2012 Todo el material que se recopila a continuación está elaborado por los alumnos de la asignatura “Recursos Tecnológicas para la Atención Educativa a la Diversidad” del curso académico 2012-2013 bajo la supervisión del profesor de la asignatura, Vicente
Gabarda Méndez, Vicente
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Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Germany and Spain lead changes towards international insolvencies in Europe [PDF]
, 2003 With the Council regulation (EC) No. 1346/2000 of 29 May 2000 on insolvency proceedings, that came into effect May 31, 2002 the European Union has introduced a legal framework for dealing with cross-border insolvency proceedings.
Wessels, Bob
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Evolution in the Design and Functionality of Rubrics: from “Square” Rubrics to “Federated” Rubrics [PDF]
, 2014 The assessment of learning remains one of the most controversial and challenging aspects for teachers. Among some recent technical solutions, methods and techniques like eRubrics emerge in an attempt to solve the situation.
Cebrian-de-la-Serna, Manuel +1 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Supervisión bancaria internacional: una doble visión BIS y EBA [PDF]
, 2012 Esta publicación se ha editado con el permiso de los Titulares de los Derechos.
Fruet Cardozo, J. Vicente +1 more
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