Results 31 to 40 of about 2,239,240 (303)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2003 Die vorliegende Arbeit ist eine repräsentative Vergleichsstudie zwischen Profit- und Non-Profit-Organisationen/Institutionen in den sechs Branchensegmenten Industrie, Verwaltung, Verkehr, Gewerbe, Unterrichtswesen und Gesundheits- und Sozialwesen in der ...
Disler, T.
core +2 more sources
Tuning Mechanical Properties of Polymeric Hydrogels Using Orthogonally Functionalized Crosslinkers
Advances in Polymer Technology, 2022 A unique orthogonal crosslinker-induced hydrogel, whose mechanical strength can be tunable by the crosslinker topology upon thermal treatment, is described herein.
Bin Liu +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The guidebook specifies the role of supervision in education, offering theoretical and practical insights that can help effectively implement supervision in educational settings.
Prysak, Dorota +2 more
core +1 more source
Investigating the core skills of clinical supervision : a qualitative analysis [PDF]
, 1998 This study used self-reports of the experience of Clinical Psychology trainees on the Doctor of Clinical Psychology course at the University of Leeds as the basis for developing a model of effective clinical supervision from the users' perspective ...
Green, David Russell
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Verzeichnis der Autorinnen und Autoren
Forum Supervision, 2014 Namen und Kontakt zu den Autorinnen und ...
Redaktion FoRuM Supervision
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source