Results 161 to 170 of about 1,045,040 (273)

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall   +8 more
wiley   +1 more source

Pulmonary arterial mechanoreceptors modulate exercise‐induced sympathetic activation in healthy humans during moderate‐intensity hypoxic exercise

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This randomized cross‐over trial (N = 12) addressed the hypothesis that selective reduction of pulmonary arterial pressure (i.e. manipulation of pulmonary arterial mechanoreceptor activation) during hypoxic exercise would reduce sympathetic outflow (muscle sympathetic nerve activity (MSNA)) in healthy humans.
Michiel T. Ewalts   +9 more
wiley   +1 more source

Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We investigated how 6 weeks of dynamic knee‐extensor interval training with blood flow restriction (BFR‐leg) and without (CTRL‐leg) impacts performance and its mechanisms using non‐invasive methods. Specifically, we used gold‐standard methods to assess neuromuscular function, vascular function using Doppler ultrasound, and near ...
Colin Lavigne   +5 more
wiley   +1 more source

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr   +15 more
wiley   +1 more source

Quantitative MRI Values for Atrial and Ventricular Parameters in Altitude‐Dwelling Youth

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 3, Page 828-845, March 2026.
ABSTRACT Background The hypoxic environment on the Qinghai Plateau significantly exacerbates myocardial remodeling, with sex/ethnicity‐specific variations in cardiac parameters among local youth. Current cardiac MRI reference values lack data from physiologically adapted populations on this plateau.
Xiumei Xiao, Hui Xu
wiley   +1 more source

Exploring the Dynamics of Ischemia and Reactive Hyperemia With Skeletal Muscle Blood Oxygen Level Dependent MRI in Patients With Peripheral Artery Disease, Age‐Matched Controls, and Young Healthy Subjects

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 3, Page 813-825, March 2026.
ABSTRACT Background Skeletal muscle blood oxygen level dependent (BOLD) MRI is a technique for assessing vascular function in peripheral limbs. In patients, however, an increased frequency of atypical response patterns has been observed, warranting investigation into its underlying causes.
Jonathan Arvidsson   +5 more
wiley   +1 more source

Measurement and management of adult blood pressure in the peri‐operative period: updated guidelines from the Association of Anaesthetists and the British and Irish Hypertension Society

open access: yesAnaesthesia, Volume 81, Issue 3, Page 402-414, March 2026.
Summary Introduction Maintaining stable blood pressure during surgery is a key responsibility of anaesthetists. Peri‐operative omission and reintroduction of antihypertensive drugs, general anaesthesia, neuraxial and regional techniques can all cause significant fluctuations in blood pressure, particularly in patients with hypertension. Since the first
Terry McCormack   +7 more
wiley   +1 more source

Resting Cerebrovascular Haemodynamics and Dynamic Assessment of Cerebrovascular Function in Polycystic Ovary Syndrome

open access: yesClinical Endocrinology, Volume 104, Issue 3, Page 245-254, March 2026.
ABSTRACT Objective Despite an increased cerebrovascular disease risk, the impact of Polycystic Ovary Syndrome (PCOS) on cerebrovascular haemodynamics and function is unknown. This study characterised cerebrovascular haemodynamics and function in women with PCOS versus healthy controls. Design Case‐control study.
Cory T. Richards   +13 more
wiley   +1 more source

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