Results 171 to 180 of about 1,045,040 (273)

Cerebrovascular regulation dynamics and Alzheimer's neuroimaging phenotypes

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Cerebrovascular dysfunction may contribute to Alzheimer's disease (AD) pathogenesis. We examined how novel cerebral hemodynamic markers relate to neuroimaging phenotypes associated with AD dementia in cognitively impaired and unimpaired older adults.
Amaryllis A. Tsiknia, Jamie A. Terner, Zoe E. Tsokolas, Dae C. Shin, Elizabeth B. Joe, Peter S. Conti, Rebecca J. Lepping, Brendan J. Kelley, Rong Zhang, Sandra A. Billinger, Helena C. Chui, Vasilis Z. Marmarelis, Meredith N. Braskie   +12 more
wiley   +1 more source

Deep cervical lymphatic–venous anastomosis attenuates cognitive dysfunction and biomarker abnormalities in severe Alzheimer's disease: A prospective single‐arm study

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION This study evaluated the efficacy of deep cervical lymphatic–venous anastomosis (dcLVA) for severe Alzheimer's disease (AD). METHODS A total of 139 severe AD patients undergoing dcLVA were enrolled, and changes in cognitive function and biomarkers were evaluated by comparing preoperative measures with postoperative outcomes over a
Xiaohong Fu, Jing Zhang, Qiuxia Xiao, Tingting Li, Qijun Li, Shaofu Zhang, Wen Zeng, Min Gong, Pan Cai, Zhaojian Deng, Xuan Zhang, Yuanjun Xin, Liping Su, Xiaohe Tian, Kaifeng Wu, Liulin Xiong   +15 more
wiley   +1 more source

Neurogenic orthostatic hypotension in Parkinson's disease: evaluation, management, and emerging role of droxidopa

Vascular Health and Risk Management, 2014
Stuart H Isaacson, Julia Skettini Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton, FL, USA Abstract: Neurogenic orthostatic hypotension (nOH) is due to failure of the autonomic nervous system to regulate blood pressure in
Isaacson SH, Skettini J
doaj  

An experimental medicine protocol for exploring the haemodynamic effects of dual agonism at the glucagon‐like peptide‐1 and glucagon receptor in healthy subjects

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 579-588, February 2026.
Aims Glucagon‐like peptide‐1 (GLP‐1) and glucagon dual receptor agonists are in clinical development for a range of metabolic conditions, including type 2 diabetes and obesity. The cardiovascular actions at these receptors are well studied, but less is known about their combination.
James Goodman, Victoria E. Parker, Carmel M. McEniery, Giovanni Di Stefano, Annette Hubsch, Evangelia Vamvaka, Jo Helmy, Fotini Kaloyirou, Navazh Jalaludeen, Peter Barker, Lutz Jermutus, Joseph Cheriyan, Philip Ambery, Ian B. Wilkinson   +13 more
wiley   +1 more source

Haemodynamic determinants of supine hypertension in patients with classical orthostatic hypotension. [PDF]

J Hypertens
van der Stam AH, Gagaouzova BS, Kerkhof FI, van Rossum IA, Shmuely S, Reijntjes RH, van Houwelingen MJ, Thijs RD, van Dijk JG.   +8 more
europepmc   +1 more source

Heat Therapy: Targeting Health, Disease, and Disability

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey, Robert D. Hyldahl, Brendan W. Kaiser, Paige C. Geiger, John R. Halliwill, Christopher T. Minson   +5 more
wiley   +1 more source

Skeletal Muscle Mass Modifies the Prognostic Impact of LDL Cholesterol in Chronic Heart Failure

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Dyslipidaemia is among the major risk factors for atherosclerotic cardiovascular disease. Paradoxically, higher cholesterol levels are associated with better survival in heart failure (HF) of any aetiology. Because cholesterol is an integral component of skeletal muscle structure, one possible explanation involves the interplay ...
Ryosuke Sato, Tania Garfias‐Veitl, Guglielmo Fibbi, Mirela Vatic, Wolfram Doehner, Stefan D. Anker, Stephan von Haehling   +6 more
wiley   +1 more source

Multimodal Management of Supine Hypertension With Orthostatic Hypotension in an Elderly Male Patient With Parkinson's Disease. [PDF]

Cureus
Dayal M, Shah MS, Radfar N, Patel S, Thomas R.   +4 more
europepmc   +1 more source

Pulmonary Obstruction and Age, Not Activity, Associate With Muscle Oxidative Impairment in Smokers With and Without COPD

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Low muscle oxidative capacity is an extrapulmonary manifestation of chronic obstructive pulmonary disease (COPD) with unclear aetiology. We sought to characterize locomotor muscle oxidative capacity in never smokers and ever smokers with and without COPD and determine clinical and behavioural features associated with low muscle ...
Alessandra Adami, Fenghai Duan, Robert A. Calmelat, Zeyu Chen, Richard Casaburi, Harry B. Rossiter   +5 more
wiley   +1 more source

Treating Numbers or Patients? Rethinking Supine Hypertension in Hospitalized Adults. [PDF]

Arq Bras Cardiol
Teixeira C.
europepmc   +1 more source