Results 101 to 110 of about 266,914 (309)

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Reproducibility of optic disk evaluation in supine subjects with a Heidelberg Retina Tomograph II laser tomographic scanner

Clinical Ophthalmology, 2016
Yosuke Harada,1 Tomoyuki Akita,2 Joji Takenaka,1 Yuko Nakamura-Kadohiro,1 Junko Tanaka,2 Yoshiaki Kiuchi1 1Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, 2Department of Epidemiology, Infectious Disease Control and
Harada Y, Akita T, Takenaka J, Nakamura-Kadohiro Y, Tanaka J, Kiuchi Y   +5 more
doaj  

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Study on relationship between decubitus position of severe patients with mechanical ventilation and their central venous pressure

Huli yanjiu, 2023
ObjectiveTo explore relationship between decubitus position of severe patients with mechanical ventilation and their central venous pressure（CVP）.MethodsNine severe patients with mechanical ventilation admitted to department of critical care medicine of ...
LI Meichen, CHEN Xunting, QIU Lixia
doaj  

The Relationship between Inferior Vena Cava Distensibility and Arterial Blood Pressure [PDF]

, 2011
The purpose of this study was to clarify the relationship between the inferior vena cava distensibility and blood pressure. Six Japanese healthy males volunteered to participate in this study.
Arakane Keita, Nishimura Kazuki, Onodera Sho, Saito Tatsuya, Seki Kazutoshi, Takahara Terumasa, Yoshioka Akira   +6 more
core   +1 more source

Is it possible to establish reference values for ankle muscle isokinetic strength? A meta-analytical study [PDF]

, 2014
BACKGROUND: The importance of measuring ankle muscle strength (AMS) has been demonstrated in a variety of clinical areas. Much data has been accumulated using the Cybex Norm isokinetic dynamometer but a uniform framework does not exist.
Fish, M, Killey, J, Milligan, J
core   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Flank free modified supine position: A new modification for supine percutaneous nephrolithotomy

Arab Journal of Urology, 2012
Percutaneous nephrolithotomy (PCNL) is the standard management for large and/or complex urolithiasis, but the standard patient position for PCNL is undecided. With the patient prone PCNL has several drawbacks, while when supine, as described previously, PCNL has mechanical limitations.
Desoky, Esam A.E., Allam, Mohammed N., Ammar, Mostafa K., Abdelwahab, Khaled M., Elsaid, Diab A., Fawzi, Amr M., Alayman, Ahmed A., Shahin, Ashraf M.S., Kamel, Hussein M.   +8 more
openaire   +2 more sources

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Toward Automation of the Supine Pressor Test for Preeclampsia [PDF]

, 2019
Preeclampsia leads to increased risk of morbidity and mortality for both mother and fetus. Most previous studies have largely neglected mechanical compression of the left renal vein by the gravid uterus as a potential mechanism.
Acharya, Aditi, Anderson, Jennifer L., Bennett, Rachel D., Bosinski, Brett M., Cox, Abigail D., Goergen, Craig J., Haas, David M., Ma, Jessica L., Qureshi, Hamna J., Reuter, David G., Wodicka, George R.   +10 more
core   +1 more source