Results 61 to 70 of about 176,026 (261)

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Chronic subdural hematoma: Influence of head position (head low/supine) postoperatively on recurrence rate after burr hole craniotomy

Journal of the Scientific Society, 2014
Introduction and Objective: Chronic subdural hematoma is the most common traumatic intra-cranial hemorrhage in elderly. It has serious morbidity and mortality, but good surgical prognosis.
Tanay Upendra Sholapurkar, Shambhulingappa Shrishal Mahantashetti, Rajesh Yashwant Shenoy, Raviraj Shambhajirao Ghorpade, Praful Suresh Maste   +4 more
doaj   +1 more source

Thoracoscopic Esophagectomy in Supine Position

Journal of Minimally Invasive Surgical Sciences, 2015
Background: Esophageal cancer needs major surgery due to its anatomic position, which is followed by high morbidity in most patients. Thoracotomy, a previously used method, was accompanied by high pulmonary complications, had physical limitations, and low tolerance of patients.
Abbas Abdollahi, Mohammad Alipour, Alireza Tavassoli, Ali Jangjoo   +3 more
openaire   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

A Portable Soft Robotic Glove with Fully Functional Thumb Assistance for Complex Dexterous Fine Motor Skills

Advanced Science, EarlyView.
A portable, sensorized, and controlled dexterous thumb‐enhanced glove helps stroke survivors swipe phones, twist caps, and perform other tasks. It is based on a powerful continuously, segmented origami dual chamber actuator to achieve active thumb CMC and MCP joint assistance and passively extend the IP joint.
Disheng Xie, Zhen Wang, Zhongping Ye, Minghao Liu, Xiangqian Shi, Shuk Fan Tong, Jianbin Liu, Chuanbin Mao, Thomas W. Leung, Haitao Liu, Raymond Kai‐yu Tong   +10 more
wiley   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source

Supine versus Prone Percutaneous Nephrolithotomy in renal stone > 2cm [PDF]

Al-Azhar International Medical Journal
Background: Percutaneous nephrolithotomy (PCNL), introduced in 1976, is the standard treatment for large kidney stones, with supine and prone positions providing different benefits and limitations.
Bahaa Eldin Ahmed, Gamal Morsi, Yaser Abdelsalam, Alaa Mahmoud   +3 more
doaj   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Reproducibility of optic disk evaluation in supine subjects with a Heidelberg Retina Tomograph II laser tomographic scanner

Clinical Ophthalmology, 2016
Yosuke Harada,1 Tomoyuki Akita,2 Joji Takenaka,1 Yuko Nakamura-Kadohiro,1 Junko Tanaka,2 Yoshiaki Kiuchi1 1Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, 2Department of Epidemiology, Infectious Disease Control and
Harada Y, Akita T, Takenaka J, Nakamura-Kadohiro Y, Tanaka J, Kiuchi Y   +5 more
doaj  

Changes in Intraocular Pressure While Using Electronic Devices in Sitting and Supine Positions

Journal of Health Science and Medical Research (JHSMR)
Objective: This study aimed to compare intraocular pressure (IOP) measurements in sitting and supine positions while exposed to electronic devices. Material and Methods: A total of 26 participants (52 eyes) had their IOP measured by Keeler Pulairs ...
Fatin Nur Najwa Norazman, Syaripah Nur Hazirah Mohd Azmi   +1 more
doaj   +1 more source