Results 241 to 250 of about 5,380,005 (311)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Errors in Results and Supplement.

JAMA Pediatr
europepmc   +1 more source

Transforming a fragile protein helix into an ultrastable scaffold via a hierarchical AI and chemistry framework. [PDF]

Elife
Qiu J, Tang G, Feng T, Zheng B, Liu Y, Zheng P.   +5 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Bridging the Scales via Personalized Cellular Modeling and Deep Phenotyping in Schizophrenia.

JAMA Psychiatry
Raabe FJ, Popovic D, Vetter C, Fischer LE, Hasanaj G, Karsli B, Schäfer TJ, Almeida V, Atella A, Gagliardi M, Boudriot E, Yakimov V, Trastulla L, Jiang T, Weyer C, Roell L, Moussiopoulou J, Krcmár L, Galinski S, Papazova I, Pogarell O, Hasan A, Schulte EC, Schmitt A, Koutsouleris N, Levina A, Wagner E, Rossner MJ, Papiol S, Falkai P, Keeser D, Ziller MJ, CDP Working Group.   +32 more
europepmc   +1 more source

Book Review Supplement Summer 2004 [PDF]

, 2015

core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Structural mechanisms of pump assembly and drug transport in the AcrAB-TolC efflux system. [PDF]

Elife
Ge X, Gu Z, Wang J.
europepmc   +1 more source

Bullying, State Policy, and Mental Health Symptoms in Gender-Diverse Youths.

JAMA Netw Open
Hughes DE, Zapetis SL, Mordy A, Lopez D, Calderon V, Adery L, Martino R, Chang SE, Uddin LQ, Cardenas-Iniguez C, Lebeau RT, Ramos N, Ng LC, Karlsgodt KH, Bearden CE.   +14 more
europepmc   +1 more source