Results 71 to 80 of about 5,380,005 (311)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

supplemental data

, 2020
Supplemental Data The differentially expressed genes (DEGs) of heart tissue between the wildtype and knockout mice responses pressure over-load.
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Synergistic effects of Mediterranean diet combined with phytosterol-based supplements and omega-3 fatty acids on lipid profiles: a pilot study in menopausal women

Frontiers in Nutrition
ObjectivesMenopause marks the cessation of ovarian function, preceded by perimenopause, a transitional phase characterized by hormonal fluctuations and metabolic changes, including dyslipidemia. Therefore, a targeted nutritional approach is essential. In
Fabiana Cannella, Elisa Assunta Algaria, Kashi Brunetti, Kashi Brunetti, Simona Del Quondam, Diego Bottan, Davide Cervia, Elisabetta Catalani   +7 more
doaj   +1 more source

Effect of white kabesak (Acacia leucophloea Roxb) leaves level in the diet on feed intake and body weight gain of Kacang goat

Journal of the Indonesian Tropical Animal Agriculture, 2017
This study was conducted to analysis the effect of levels of white kabesak (Acacia leucophloea Roxb.) Willd. leaves in the diet on feed intake, digestibility and body weight gain of Kacang goats.
E. D. W. Lawa, M. Marjuki, H. Hartutik, S. Chuzaemi   +3 more
doaj   +1 more source

Zinc Deficiency in Men Over 50 and Its Implications in Prostate Disorders

Frontiers in Oncology, 2020
Research has been consistently showing the role of zinc (Zn) in prostate function. In this article, we review the current literature on the anatomy and main functions of the prostate, highlighting the role of zinc.
Ann Katrin Sauer, Ann Katrin Sauer, Ann Katrin Sauer, Hector Vela, Guillermo Vela, Guillermo Vela, Peter Stark, Eduardo Barrera-Juarez, Andreas M. Grabrucker, Andreas M. Grabrucker, Andreas M. Grabrucker   +10 more
doaj   +1 more source

Advancement, Spring 2003 [PDF]

, 2003
Advancement, a supplement to Bostonia magazine, provided updates on BU development activities, including major gifts and ...
Boston University Office of Development and Alumni Relations
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Collagen supplementation and regenerative health: advances in biomarker detection and smart material integration

Frontiers in Nutrition
Collagen, the most abundant structural protein in the human body, plays a key role in skin integrity, tissue repair, and extracellular matrix organization. With increasing consumer and clinical interest, collagen supplementation has expanded rapidly, yet
Tatjana Ivaskiene, Jonas Viskelis, Paulina Streimikyte, Milda Savickaitė, Ali Mobasheri, Ali Mobasheri, Ali Mobasheri, Ali Mobasheri, Greta Kaspute   +8 more
doaj   +1 more source