Applying total cost of ownership for strategic procurement : three industrial case studies. [PDF]
In this paper we elaborate on a Total Cost of Ownership supplier selection methodology that we have constructed using three real life case studies which are presented in this article.
Degraeve, Zeger +2 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Impact of “Product Scope” and “Customer Scope”
The two most important approaches toward the diversification strategy for suppliers are extending “product scope” (product range) and “customers scope” (customer reach) within the same industry.
Yoshinori KONNO
doaj +1 more source
Portfolios of Exchange Relationships: An Empirical Investigation of an Online Marketplace for IT Services [PDF]
Small firms face distinct problems and opportunities when procuring IT resources. Whereas previous work focused at the level of firm or buyer-supplier dyad, we address portfolios of buyer-supplier relationships at an online marketplace for IT services ...
Heck, H.W.G.M. van +2 more
core +1 more source
Supplier Development: Performance Improvement Program [PDF]
Flow chart describing Verité’s guided-change approach toward strengthened supplier ...
Verité
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
ALGORITHM OF PREPARING ANALYTICAL INFORMATION FOR PURCHASING ACTIVITY
Objective: to substantiate and develop the stages of the analytical information preparation for negotiations on cost reduction for purchasing activity. Methods: systemic analysis, inductive and deductive methods.
S. G. Demchenko +2 more
doaj
ASPECTS OF THE RELATIONSHIPS OF THE COMPANIES WITH THE SUPPLIERS [PDF]
Nowadays the management of the relationships with the suppliers is a key factor for successful business. The objective of this research is to highlight the aspects of the relationships between the commercial and manufacturing companies and their ...
Plamena Milusheva
doaj
Domination of World’s Leading Retailer- Wal-Mart, “Save Money, Live better”; Workers’ nightmare [PDF]
The report describes living and working conditions at the Hantai Shoe factory in Shenzhen City, China, a Walmart ...
China Labor Watch
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

