Results 111 to 120 of about 645,023 (277)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Pricing in a duopoly with a lead time advantage [PDF]
We analyze the price competition between two suppliers offering two different lead times and two different prices to a buyer. The buyer chooses its inventory replenishment policy in order to minimize its infinite-horizon average cost.
Martinez de Albeniz, Victor
core
Waiting for Leviathan: A Note on \u3cem\u3eModern Wo\u27er Trading Co Ltd v Ministry of Finance of the People\u27s Republic of China\u3c/em\u3e [PDF]
, 2013 This article analyzes a Chinese bid protest that has taken nearly seven years to adjudicate, yet as of this writing, no institution of the Chinese state has evaluated the substance of the protester’s bid challenge.
Mitterhoff, Daniel J.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Hybrid Methods for Selecting Precast Concrete Suppliers Based on Factory Capacity
Applied SciencesSupplier selection is one of the critical processes that entail multiple complex deliberations. The selection of an appropriate alternative supplier is a highly intricate process, primarily due to there being multiple criteria which are exceptionally ...
Mohammed I. Aldokhi +3 more
doaj +1 more source
R&D incentives and spillovers in a two-industry model [PDF]
This paper develops a two-industry model of R&D. A monopolist supplier sells an intermediate good to an oligopolistic buyer industry where firms compete in quantity and quality-enhancing R&D. The supplier can contribute to downstream product improvements
Harhoff, Dietmar
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Home Depot Foundation - 2009 Annual Report [PDF]
, 2010 Contains videos of president's message, 2008 highlights, and national impact; program information; grantee profiles; grant information by state; awards; and lists of corporate donors, board members, staff, and supplier advisory committee ...
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Effects of full transparency in supplier selection on subjectivity and bid quality [PDF]
, 2010 In this paper, we highlight a number of problems arising with a commonly used supplier selection method: the weighted factor score method. We discuss the behaviour of this method with respect to weighting, scaling issues, and relative scoring.
Schotanus, Fredo, Telgen, Jan
core +1 more source