Results 151 to 160 of about 301,305 (357)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Supplier Selection and Order Allocation in A Pharmaceutical Wholesaler
Jurnal Teknik IndustriSupplier selection is essential for any organization , as it plays a significant role in enhancing productivity. This study focuses on a local pharmaceutical wholesaler (PW) company, which places orders with other local PWs to meet its demand. Typically,
Ryan Hikmah Fadilla +2 more
doaj +1 more source
A multi-stage group decision making approach for sustainable supplier selection based on probabilistic linguistic time-ordered incentive operator. [PDF]
PLoS One, 2023 Zhang F, Li M, Ye Z, Niu Y.
europepmc +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A Markovian-based fuzzy decision-making approach for the customer-based sustainable-resilient supplier selection problem. [PDF]
Soft comput, 2023 Tavakoli M +3 more
europepmc +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Extended Multicriteria Group Decision Making with a Novel Aggregation Operator for Emergency Material Supplier Selection. [PDF]
Entropy (Basel), 2023 Liu L, Zhu Q, Yang D, Liu S.
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
360This study examined the impact of risk management strategies on supplier selection at the Lower Benue River Basin Development Authority (LBRBDA) in Makurdi. It was motivated by the growing importance of effective supplier selection in public procurement
Aondofa Tyozenda +2 more
doaj +1 more source