Results 291 to 300 of about 301,305 (357)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Distributed Search Algorithm for Supplier Selection

, 2014
FU Li-ku
openalex   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Applying Failure Mode and Effects Analysis to Supplier Selection

, 2010
Cliff Welborn
openalex   +1 more source

A Latent Space-Based Multivariate Capability Index: A New Paradigm for Raw Material Supplier Selection in Industry 4.0

Alberto Ferrer, Joan Borràs‐Ferrís, Carl Duchesne   +2 more
openalex   +1 more source

Supplier selection based on multi-criteria decision making approaches: an ımplementation in electronics sector

, 2014
Murat Arıkan, Berat Gökbek
openalex   +1 more source

Supplier Selection Process for New Norwegian Ventures

, 2017
Emilie Aabakken, Andrea Holvik Thorson
openalex   +1 more source

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Selecting Startups as Suppliers: A Typology of Supplier Selection Archetypes

Journal of Supply Chain Management, 2020
Recent research highlights opportunities to study collaborations between established firms and startups from a buyer–supplier relationship perspective. However, before firms can leverage startups’ resources and capabilities in a buyer–supplier relationship, they need to identify, evaluate, and select suitable startups as their suppliers.
Stefan Kurpjuweit, Stephan M. Wagner, Thomas Y. Choi   +2 more
openaire   +1 more source