Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Apparatus for supplying conditioned air at a substantially constant temperature and humidity [PDF]
, 1980 The apparatus includes a supply duct coupled to a source of supply air for carrying the supply air therethrough. A return duct is coupled to the supply duct for carrying return conditioned air therethrough. A temperature reducing device is coupled to the
Obler, H. D.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multi-Agent System Interaction in Integrated SCM\ud [PDF]
, 2009 Coordination between organizations on strategic, tactical and operation levels leads to more effective and efficient supply chains. Supply chain management is increasing day by day in modern enterprises..
Purohit, G. N. +2 more
core +1 more source
Military Contacts of the Polish-Lithuanian Commonwealth and the Duchy of Prussia in the First Years of the Livonian War (1600-1602) [PDF]
Codrul Cosminului, 2018 The author discusses Polish-Prussian alliance and conflicts caused by the war with Sweden over Estonia and Livonia. The subject of the article is the first period of the war (1600-1602).
Dariusz Milewski
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Agency Theory and Supply Chain Management: Goals and Incentives in Supply Chain Organisations [PDF]
, 2007 Purpose Agency theory (AT) offers opportunities to examine how the risk of opportunism can be prevented or minimised along supply chain organisations using incentives to achieve goal alignment. Methodology The study presents evidence of how members of
Hornibrook, Susan A.
core
Feed safety in the feed supply chain [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2011 A number of issues have weakened the public's confidence in the quality and wholesomeness of foods of animal origin. As a result farmers, nutritionists, industry and governments have been forced to pay serious attention to animal feedstuff production ...
Pinotti, L., Dell'Orto, V.
doaj