Results 161 to 170 of about 6,284,717 (313)

Short supply [PDF]

Nature, 2003
openaire   +2 more sources

Drug supply chain disruptions and outpatient medication shortages in the Veterans Health Administration, 2017-2020. [PDF]

Explor Res Clin Soc Pharm
Aspinall SL, Kima C, Zhao X, Thorpe CT, Cunningham FE, Gellad WF, Glassman PA, Good CB, Martin J, Tadrous M, Suda KJ.   +10 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An empirical network study of the antimalarial supply chain in Ghana. [PDF]

PLoS One
Adams O, Wang CL, Chattoe-Brown E, Hamill H, Hampshire K, Mariwah S, Amoako-Sakyi D, Johnson FA, Ackland GJ.   +8 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Supply chain carbon reduction considering consumer skepticism and blockchain technology under the cap-and-trade policy. [PDF]

PLoS One
Yuan PP, Wang Q.
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Addressing Parental Supply of Alcohol to Teens: Development and Message Testing of the Keep Their Future Bright Campaign. [PDF]

Health Promot J Austr
Harding N, Chenery M, McPhie S, Fredheim S, Bovopoulos N, Martin C, Marrocco C.   +6 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Retraction: Inclined analysis of water diversion project supply chain profits in the occurrence of whole supply chain damage in undeveloped regions of China. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source