Results 191 to 200 of about 6,656,292 (362)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

How metaverse-enabled digital transformation drives sustainable supply chain innovation: evidence from Pakistan's textile industry. [PDF]

Sci Rep
Abdullah M, Ullah A, Jamal MF, Aldakheel EA, Khafaga DS, Ashraf S, Rasool Z.   +6 more
europepmc   +1 more source

A taxonomical study of agility strategies and supporting supply chain management practices

, 2011
Rundong Wang
openalex   +1 more source

Key Performance Indicators in Emerging Supply Chain of Mangosteen in Bogor District, West Java Province, Indonesia

, 2017
Retno Astuti, Marimin Marimin, Machfud, Roedhy Poerwanto, Yandra Arkeman   +4 more
openalex   +1 more source

Surface water supply of the United States, 1961-65: Part 5. Hudson Bay and upper Mississippi River basins: Volume 2. Upper Mississippi River basin above Keokuk, Iowa [PDF]

, 1971
U.S. Geological Survey
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Digital intelligence technology adoption and supply chain security of manufacturing firms: empirical evidence from China. [PDF]

Sci Rep
Yu Z, Liu H, Xing C.
europepmc   +1 more source

Supply chain turbulence: the impact of a mid-range event in multi-tier, multi-dimension supply chains

, 2015
Janaina Siegler Marques Batista
openalex   +1 more source

Code to reproduce Figures in "Adapting to Disruptions: Managing Supply Chain Resilience through Product Rerouting"

, 2023
Ambra Amico, Luca Verginer, Giacomo Vaccario, Giona Casiraghi, Frank Schweitzer   +4 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source