Results 261 to 270 of about 6,656,292 (362)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Navigating Drug Shortages in Obstetric Care. [PDF]

O G Open
Piltch G, Rochelson D, Rochelson B.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A Comprehensive Approach to Days' Supply Estimation in a Real-World Prescription Database: Algorithm Development and Validation Study. [PDF]

Online J Public Health Inform
Malk M, Mooses K, Oja M, Holm J, Keidong H, Umov N, Tamm S, Reisberg S, Vilo J, Kolde R.   +9 more
europepmc   +1 more source

Mining Company's Global Supply Chain - Uniformly Random Logistics Data from a Caterpillar

, 2015
Marco Veluscek, Tatiana Kalganova
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Modelling brain metabolism with interacting nonautonomous phase oscillators. [PDF]

Front Netw Physiol
Barnes SJK, Echeverría A, Hawley J, Suprunenko YF, Stefanovska A.   +4 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Beyond the grid: Navigating water supply and sanitation service ecosystems in informal settlements. [PDF]

PLoS One
Casas A, Hutchings P, Bell AR, Kupiec-Teahan B, Lewis AR, Sanchez JM, Willcock S, Anciano F, Barrington DJ, Dube M, Karani C, Llaxacondor A, López H, Mdee AL, Ofori AD, Riungu JN, Russel KC, Kristensen BR, Parker A.   +18 more
europepmc   +1 more source

Robust Supply Chains for Humanitarian Aid in Africa

, 2016
Victor Ashagbley
openalex   +1 more source