Results 121 to 130 of about 3,300,319 (310)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Den svenska supply chain-panelen: Supply chain-strategi [Elektronisk resurs]

open access: yes, 2013
I maj 2013 etablerades den svenska supply chain-panelen av forskare från Institutionen för teknisk ekonomi och logistik vid Lunds universitet LTH. Panelen består av 69 personer, som alla arbetar med supply chain-frågor, varav flertalet är medlemmar i ...
Norrman, Andreas,   +2 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Building blocks for enhancing personnel performance: activities, best practices and lessons learned from Ethiopia

open access: yesJournal of Pharmaceutical Policy and Practice, 2014
Daniel Taddesse   +3 more
doaj   +1 more source

Green House Gas Emission Analysis in the Food Processing Industry: A Case Study of MSME in South India

open access: yesEngineering Proceedings
Rising carbon emissions are worsening global climatic conditions, posing a grave threat to the environment. Analysing and reducing carbon footprints are vital for combating climate change.
Gangavarapu Chenchu Chythanya Krishna   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Strategic Fit of Supply Chain Integration in the TFT-LCD Industry

open access: yes, 2012
[[abstract]]Purpose - The purpose of this paper is to identify what kind of supply chain integration strategies can support TFT-LCD manufacturers seeking to break through the cost constraints and complex co-operation relationships between manufacturers ...
沙永傑;D.Y.Sha;P.K.Chen;陳永信;Chen, Yung-Hsin
core  

Liner Schedule Design under Port Congestion: A Container Handling Efficiency Selection Mechanism

open access: yesJournal of Marine Science and Engineering
Port congestion significantly impacts the reliability of container ship schedules. However, the existing research often treats vessel time in port as a random variable, failing to systematically consider the complex impact of port congestion on ship ...
Haibin Qu   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Developing supply chain maturity [PDF]

open access: yes
This study introduces an empirical model of supply chain maturity and assesses its impact upon performance. Findings suggest that supply chain maturity is multi-dimensional including the areas of planning, sourcing, making, delivering, new product ...
Done, Adrian
core  

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