Results 121 to 130 of about 1,687,730 (310)

THE “DARK” AND THE “BRIGHT” SIDES OF POWER IN SUPPLY CHAIN NETWORKS [PDF]

open access: yes
One of the prerequisites for a supply chain network is the existence of a focal company, which possesses power to coordinate the network in order to realize its strategic objectives.
Belaya, Vera, Hanf, Jon Henrich
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Measuring information security breach impact and uncertainties under various information sharing scenarios [PDF]

open access: yes, 2013
This study draws on information theory and aims to provide simulated evidence using real historical and statistical data to demonstrate how various levels of integration moderate the impact and uncertainties of information security breach on supply chain
Chan, Hing   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Building blocks for enhancing personnel performance: activities, best practices and lessons learned from Ethiopia

open access: yesJournal of Pharmaceutical Policy and Practice, 2014
Daniel Taddesse   +3 more
doaj   +1 more source

Supply Chain Management of Fresh Produce: Melons in Western China [PDF]

open access: yes
The western part of China has a long history and reputation of growing a variety of quality melons largely due to its semi arid agronomic environment.
Qiao, Zhixia   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The relation between supply chain performance and supply chain governance practices [PDF]

open access: yes
The relation between corporate governance practices and firms’ performance is a common research subject for academics. This article goal is to present theoretical details regarding the possible relation between supply chain governance practices and ...
Emil CRIȘAN   +2 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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