Results 81 to 90 of about 3,718,232 (314)
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Overview and classification of coordination contracts within forward and reverse supply chains [PDF]
Among coordination mechanisms, contracts are valuable tools used in both theory and practice to coordinate various supply chains. The focus of this paper is to present an overview of contracts and a classification of coordination contracts and ...
Govindan, Kannan, Popiuc, Maria Nicoleta
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
, 2021 Supply chain management has recently received considerable attention with an aim to reduce production costs, manage risks, reduce delays, maximize profit, and improve the quality of products, with the result of increased competitiveness and profitability
Agarwal, R, Subramani, P
core
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Supply Chain Coordination with Guaranteed Auction Contracts
MathematicsThis paper investigates the problem of contract coordination in a two-tier multi-unit auction supply chain consisting of a seller and an auction house.
Xinyu Geng, Jiaxin Wang
doaj +1 more source
Optimal decisions and comparison of VMI and CPFR under price-sensitive uncertain demand
Journal of Industrial Engineering and Management, 2013 Purpose: The purpose of this study is to compare the performance of two advanced supply chain coordination mechanisms, Vendor Managed Inventory (VMI) and Collaborative Planning Forecasting and Replenishment (CPFR), under a price-sensitive uncertain ...
Yasaman Kazemi, Jun Zhang
doaj +1 more source
Medical service pricing and pharmaceutical supply chain coordination contracts under the zero-markup drug policy. [PDF]
Front Public Health, 2023 Zhou N, Li S, Zhao G, Li C, Yu N.
europepmc +1 more source