Results 31 to 40 of about 58,819 (265)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Identify and analyze strategies for supply chain resilience [PDF]
مطالعات مدیریت راهبردیIntroductionSeveral disruptions in the business environment can occur naturally or by unnatural causes. Due to the destructive effects of disasters, crises, natural and unnatural disasters on supply chain performance, organizational experts seek to study
Somayeh Eslami Farsani +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Supply Chain Analytics, 2023 Mass vaccination programs should employ effective strategies to design a resilient vaccine supply chain for immunizing populations quickly and efficiently.
Kasuni R.R. Gomes +3 more
doaj +1 more source
Disruption cascades in supply chain networks [PDF]
, 2018 Supply chain disruptions result in substantial losses that can arise not only due to direct shocks at firms (eg., due to natural disasters or factory fires), but also from the interruption of normal operations at the suppliers' or buyers' ends; that is, due to disruptions cascading from supply chain partners in the adjacent tiers and beyond. The extent
openaire +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Pricing Decisions of a Dual-Channel Supply Chain considering Supply Disruption Risk
Discrete Dynamics in Nature and Society, 2018 Supply disruption may cause strong complaints of customers, which is a cost loss for the firms in the supply chain. Obviously, if realizing that there is the disruption risk, the members in a supply chain will adjust their decisions.
Yancong Zhou +3 more
doaj +1 more source
IEEE Access, 2021 Supply chain resilience is the key for cross-border e-commerce enterprises to continuously obtain competitive advantages. This paper studies the influencing factors of cross-border e-commerce supply chain resilience (CBSCR), so as to further enhance the ...
Xianli Liu, Zhiwu Dou, Wei Yang
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source