Results 241 to 250 of about 17,906 (305)

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

open access: yesAdvanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud   +12 more
wiley   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

open access: yesAdvanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu   +10 more
wiley   +1 more source

Explainable AI augmented retailer segmentation using knowledge graph. [PDF]

open access: yesSci Rep
Shiralkar K   +4 more
europepmc   +1 more source

Supply chain financing in agriculture

open access: yes
R. Samson Arun Prem Kumar   +2 more
openaire   +1 more source

The practice of drug emergency supply in China during the COVID-19 pandemic: A policy mix perspective. [PDF]

open access: yesPLoS One
Jie-Ying Z   +7 more
europepmc   +1 more source

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