Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok +4 more
wiley +1 more source
From Cosmetic Abuse to Clinical Mismanagement: A National Simulated Patient Study Assessing Community Pharmacists' Stewardship of Topical Corticosteroids in Jordan. [PDF]
Abdel-Qader DH +9 more
europepmc +1 more source
Chlorine‐Free Depolymerization of Commercial PMMA via Oxygen‐Centered Radicals
A new chlorine‐free photothermal method enables sustainable recycling of plastics with C–C backbones under mild conditions. Driven by an oxygen‐centered radical pathway with ppm levels of anthraquinone catalyst, it eliminates hazardous chlorinated solvents, achieving an impressive 97% depolymerization conversion.
Chih‐Yin Lin +5 more
wiley +1 more source
Optimization of drug delivery in internet hospitals using the 5M1E and HACCP frameworks. [PDF]
Cheng JJ +7 more
europepmc +1 more source
Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez +6 more
wiley +1 more source
Expanding access to prehospital blood products: a narrative review of clinical evidence, systems barriers, and statewide strategies. [PDF]
Geracci JP +13 more
europepmc +1 more source
Borylcyclopropanes: Synthetic Strategies and Applications
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley +1 more source
Untangling the role of blockchain technology in shaping supply chain concentration from the contingency and configuration perspectives. [PDF]
Zhang J +5 more
europepmc +1 more source
Remapping the Synthetic Landscape of α‐Tertiary Alkylamines via Dual‐Functional Catechol
A three‐component assembly strategy has been developed for the modular synthesis of hindered α‐tertiary aliphatic amines from readily available precursors through unlocking the dual role of catechol. The practicality of this methodology has been demonstrated in over 90 examples, including compounds that are otherwise difficult to access, along with ...
Chen‐Yan Cai, Yuzuru Kanda, Tian Qin
wiley +1 more source
The One Health Trail: Physician Leaders as Advocates for Human, Animal, and Environmental Health. [PDF]
Habermehl N +6 more
europepmc +1 more source

