Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Evolution of Supply Chain Collaboration: Implications for the Role of Knowledge [PDF]
Increasingly, research across many disciplines has recognized the shortcomings of the traditional “integration prescription” for inter-organizational knowledge management.
Farris, M. Theodore, Gravier, Michael
core +1 more source
Risk Minimisation in Integrated Supply Chains [PDF]
Abstract Integrated supply chains, due to their complexity, are vulnerable in relation to various types of risks, especially in the present turbulent market environment, characterised by increased demand for effectiveness of the individual logistic activities, extended customer service and decreased cost.
Strohmandl, Jan, Čujan, Zdeněk
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Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The role of interpersonal relationships in supply chain integration : a thesis by publications presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Logistics and Supply Chain Management at Massey University, Albany, New Zealand [PDF]
Chapter 2 was published as: Wang, B., Childerhouse, P., Kang, Y., Huo, B., & Mathrani, S. (2016). Enablers of supply chain integration: Interpersonal and interorganizational relationship perspectives, Industrial Management & Data Systems, 116(4), 838-855.
Wang, Bill
core
A review of supply chain integration extents, contingencies and performance : A post Covid-19 review
This research intends to synthesize and analyze the existing research published with respect to “extent of supply chain integration” and impact of Multiple extents of supply chain integration on supply chain performance.
Nadir Munir Hassan +1 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The influence of information technology integration on firm performance through supply chain quality and supply chain resilience [PDF]
Products produced by manufacturing companies are always required to meet the requirements set by customers. Manufacturing companies need to maintain product quality by involving internal company components and external partners by using integrated ...
Sautma Ronni Basana +5 more
doaj +1 more source
Supply Chain Integration [PDF]
Since its introduction by management consultants in the early 1980s, supply chain management (SCM) has been primarily concerned with the integration of processes and activities both within and between organisations. The concept of supply chain integration (SCI) is based on documented evidence that suggests that much of the waste throughout businesses ...
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

