Results 101 to 110 of about 98,884 (268)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Designing an integrated blockchain-enabled supply chain network under uncertainty. [PDF]

open access: yesSci Rep, 2023
Babaei A   +3 more
europepmc   +1 more source

Developing Supply Chain Networks - Status and Trends [PDF]

open access: yesBusiness Logistics in Modern Management, 2013
Designing, establishing and functioning of supply chain networks are key issues of all participants in the supply chain and it must be viewed in the context of strategic, tactical and operational performance of individual part icipants. Development and functioning of all business systems takes place in conditions of increasing cost pressure, growing ...
Josip Mesaric, Davor Dujak
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Identifying Key Nodes and Enhancing Resilience in Grain Supply Chains Under Drought Conditions

open access: yesSystems
Grain supply chains remain stable in the face of natural disasters, and the resilience of the grain supply chain plays an important role. In a complex scenario of exposure to shocks, it is significant to identify the critical nodes of the grain supply ...
Shuiwang Zhang, Chuansheng Zhou
doaj   +1 more source

Dynamic Modeling of a New Product Supply Chain using System Dynamics Approach [PDF]

open access: yesچشم‌انداز مدیریت صنعتی, 2017
Supply chains are network of organizations and individuals involved in fulfilling customer needs. Increasing research and interests of researchers and industrial managers in the supply chain, make it necessary to investigate the behavior of the supply ...
Ali Mohaghar   +2 more
doaj  

Viable healthcare supply chain network design for a pandemic. [PDF]

open access: yesAnn Oper Res, 2022
Alizadeh M   +4 more
europepmc   +1 more source

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