Results 121 to 130 of about 16,368,583 (255)
Improving supply chain planning with advanced analytics : analyzing lead time as a case study
Thesis: M. Eng. in Supply Chain Management, Massachusetts Institute of Technology, Supply Chain Management Program, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (pages 72-74).Over the years, supply chain management has ...
Yau, Darryl (Chun Him)
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In recent years, global supply chains face great challenges driven by events such as trade wars, the Covid-19 pandemic, and the Russia-Ukraine War. Since the disruptions caused by such shocks are more systematic and the duration is harder to predict ...
L. Jeff Hong +3 more
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
A vertically and horizontally integrated synergistic supply chain network design
The study introduces a novel Supply Chain Network Design (SCND) framework that integrates both Vertical and Horizontal SYnergies (VHSY). This approach is designed to evaluate performance with respect to cost efficiency and CO₂ emission reduction ...
Reza Lotfi +4 more
doaj +1 more source
Threonine 348 regulates the subcellular localization of PTEN
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Key supply chain integration factors for success of medical device startups
Thesis: M. Eng. in Supply Chain Management, Massachusetts Institute of Technology, Supply Chain Management Program, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (pages 60-62).Healthcare cost are on the rise and becoming a
Gupta, Sanjay, M. Eng. Massachusetts Institute of Technology
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Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
E-commerce based closed-loop supply chain for plastic recycling
Thesis: M. Eng. in Supply Chain Management, Massachusetts Institute of Technology, Supply Chain Management Program, May, 2020Cataloged from the official PDF of thesis.Includes bibliographical references (pages 73-77).The world is facing a grave plastic ...
Banerjee, Saikat,M. Eng.Massachusetts Institute of Technology.
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