Results 171 to 180 of about 269,064 (306)

Responding to and managing antibiotic shortages: a qualitative study with experts and opinion leaders. [PDF]

Wellcome Open Res
Nampoothiri V, Bhandari RK, Pandey AK, Mbamalu O, Cohn J, Singh S, Mendelson M, Shafiq N, Charani E.   +8 more
europepmc   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

The impact on healthcare facilities of the 2024 IV fluids shortage after Hurricane Helene: A mixed methods study. [PDF]

PLoS One
Gorgens S, Alshadad A, Malek A, Boukai A, Davis L, Hertelendy AJ, Issa F, Woodward C, Voskanyan A, Ciottone G.   +9 more
europepmc   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

Challenges and best practices in essential medicines supply and use in internally displaced persons (IDP) camps: A qualitative study. [PDF]

Explor Res Clin Soc Pharm
Alemayehu TT, Geremew GW, Bekalu AF, Abebe TB, Bayleyegn ZW, Bekele A, Wassie YA, Tadesse SH, Beshada MA, Feye NT, Gebremeskel ED.   +10 more
europepmc   +1 more source

Supply chain partnership based on revenue sharing

, 2003
The profit margin of retailers and suppliers are decreasing as more and more market players are joining the market. The customer generally switch to another brand / retailer as the price increases. Since supplier revenue depends upon the retailer's revenue; retailer's revenue indirectly depends upon the supplier's price and the customer demand; and ...
Chauhan, Satyaveer Singh, Proth, Jean-Marie   +1 more
openaire   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Electromagnetic Noise Characterization and Suppression in Low-Field MRI Systems. [PDF]

Magn Reson Med
Guallart-Naval T, Algarín JM, Alonso J.
europepmc   +1 more source

A Nanobody‐LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin, Zhiying Huang, Hai Huang, Yupei Zhang, Yuting Chen, Xi He, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Xiangrong Song   +9 more
wiley   +1 more source

Building long-term relationships between producers and trader groups in the non-timber forest product sector in Cameroon [PDF]

, 2012
D'Haese, Marijke, Degrande, Ann, Divine Foundjem, Tita, Facheux, C, Gyau, A, Mbosso Mafomekiet Fouedjo, Philomène Charlie, Tchoundjeu, Zac, Van Damme, Patrick   +7 more
core   +1 more source