Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Pengelolaan Rantai Pasok dan Daya Saing Kelapa Sawit di Aceh
Agraris: Journal of Agribusiness and Rural Development Research, 2016 Nowadays, supply chain management is vital for palm oil plantations, along with the increases of competitive efforts and equal partnership position between suppliers and processors.
Fajri Jakfar +2 more
doaj +1 more source
ANALISIS PERFORMANSI RANTAI PASOK KERIPIK APEL PADA UKM GAPURA DI DESA TULUNGREJO KOTA BATU [PDF]
UKM Gapura experiences problems in fluctuating prices for apples, resulting in a sense of distrust between partners, as well as supply chain channels that are sometimes unstable.
Maulana, Fariz Rimba
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Collaborative governance for the sustainable development goals [PDF]
, 2018 The advent of the UN's Sustainable Development Goals has refocused global attention on the roles of business and other nonstate actors in achieving global goals.
Ackerman +31 more
core +3 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Proposing a Conceptual Model for Supply Chain Quality Managent (SCQM) and Surveying its Position in Iran’s Car Industry Case Study: IKCO Tondar 90 Project [PDF]
مدیریت صنعتی, 2011 Nowadays companies have to have a close partnership with the other companies involved in their supply chain in order to upgrade their product quality.
Hossein Safari, Omid Mohebbimanesh
doaj
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Journal of Transport and Supply Chain ManagementBackground: South African municipalities face numerous supply chain management (SCM) challenges that limit their effectiveness and efficiency in executing their service delivery mandate.
Gladys N. Mahache +2 more
doaj +1 more source
Institutional Role In Cocoa Supply Chain And Cocoa Added Value In Bulukumba District [PDF]
BIO Web of ConferencesSupply chain institutions are management relationships or systematic working system and mutually supportive between several supply chain partnership of institutions.
Apriliani Rakhman Fira +2 more
doaj +1 more source
Interdependency modeling of supply chain risks incorporating game theoretic risks [PDF]
, 2014 Most of the current risk quantification techniques being applied in the field of Supply Chain Risk Management consider risk factors to be independent. This research considers risks as interdependent triggers, events and consequences.
Dickson, Alexander +2 more
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