Results 191 to 200 of about 3,698,291 (269)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

10-point action plan for the development and implementation of a pan-European decision support system for wildfire risk mitigation and management

Ackermann, Anne, Martinez de Arano, Inazio Maria   +1 more
openalex   +1 more source

Perceived Stress and Burnout Among Nurses in Acute and Critical Care Settings: The Mediating Role of Self-Efficacy. [PDF]

Nurs Crit Care
Lee SY, Li CY, Hsiao PC, Song CY, Lin CH, Chiang KJ, Pan HH.   +6 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

UAV-LiDAR dataset of Pangandaran coastal tourism hotspots for tsunami and climate risk valuation and exposure mapping. [PDF]

Data Brief
Syamsuddin ML, Abdurrahman U, Puspita AR, Sunarto, Sari QW, Syamsudin F, Pratyaksa IF, Cipta IM, Radjawane IM, Park H.   +9 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Supporting points processes

, 1999
openaire   +1 more source

VOLUNTARY MEMBERSHIP: UP TO WHICH POINT DOCOOPERATIVES SUPPORT LIBERALISM?

David Hiez
openalex   +2 more sources

Internet Use and Self-Rated Health Among Older Adults: Scoping Review.

Interact J Med Res
AboJabel H, Abo-Rass F.
europepmc   +1 more source