Results 41 to 50 of about 3,698,291 (269)
Automatic Detection of Delamination on Tunnel Lining Surfaces from Laser 3D Point Cloud Data by 3D Features and Support Vector Machine [PDF]
, 2022 Tsukasa Mizutani, Takahiro Yamaguchi
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Succinct Geometric Indexes Supporting Point Location Queries
Proceedings of the Twentieth Annual ACM-SIAM Symposium on Discrete Algorithms, 2009 We propose designing data structures called succinct geometric indexes of negligible space (more precisely, o ( n ) bits) that support geometric queries in optimal time, by taking advantage of the n points in the dataset permuted and stored elsewhere as a sequence. Our
Bose, Prosenjit +4 more
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Contributions of Support Point Number to Mirror Assembly Thermal Sensitivity Control. [PDF]
Sensors (Basel), 2023 Li H, Zhang H, Ding Y, Zhang J, Cai Y.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Quantification of Conflicts of Interest in an Online Point-of-Care Clinical Support Website [PDF]
, 2019 Ambica C. Chopra +5 more
openalex +1 more source
Evaluating a clinical decision support point of care instrument in low resource setting. [PDF]
BMC Med Inform Decis Mak, 2023 Tegenaw GS +5 more
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source