Results 221 to 230 of about 8,227,707 (287)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Bullying Profiles and Co-Rumination: A Latent Transition Analysis in Adolescents. [PDF]

Aggress Behav
Misas M, Camacho A, Romera EM.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Study on the influence of stress relief in close-distance coal seam Goaf and roadway excavation disturbance on surrounding rock. [PDF]

Sci Rep
Liu Z, Chen M.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Development and internal validation of a therapeutic effect predictive model for myofascial pain syndrome. [PDF]

Front Neurol
Zhu X, Cheng W.
europepmc   +1 more source

Feasibility, acceptability and effectiveness of digitally delivered multimodal prehabilitation for cancer patients: A mixed-methods systematic review. [PDF]

PLOS Digit Health
Oyedemi J, Dunne S, Brennan L, Coffey L.
europepmc   +1 more source

Automated OCT-tailored and same-visit biomarker-targeted microperimetry in geographic atrophy. [PDF]

Sci Rep
Tratnig-Frankl M, Kuchernig L, Birner K, Schürer-Waldheim S, Eidenberger A, Schrittwieser J, Gumpinger M, Faustmann G, Baratsits M, Leingang O, Reiter GS, Schmidt-Erfurth U.   +11 more
europepmc   +1 more source

A primary care approach to bereavement. [PDF]

Br J Gen Pract
Bennett L, Knights D, Langford A, Sharma S.   +3 more
europepmc   +1 more source