Results 261 to 270 of about 10,186,856 (344)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Obligate faunivorous megatheropod size class patterns across the Jurassic-Cretaceous Periods. [PDF]

PeerJ
Boisvert C, Perkins J, Morrison C, Gascoigne SJL, Holtz TR, Curtice B.   +5 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Comparative analysis of different biophysical techniques for exosome characterization. [PDF]

Sci Rep
Yu X, Wang Z, Zhang R, Guo W, Chang Q, Chu W, Zeng C, Wang L, Yu C, Li W.   +9 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Ultrasound-derived gestational sac triple product as a predictor of early medical abortion failure with mifepristone-misoprostol regimens: a retrospective cohort study. [PDF]

Front Med (Lausanne)
Xue RH, Li J, Li YX, Gu ZY, Tang D, Yang J, Fu YY, Chen XL, Liu P.   +8 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Seasonal variability of the microzooplankton biomass and community composition on the Northeast US Shelf. [PDF]

J Plankton Res
Lopez F, Marrec P, Menden-Deuer S.
europepmc   +1 more source

Feasibility of starting a clothing company of street line clothes for ladies in large sizes in the city of bucaramanga, with technological support in electronic commerce.

, 2010
Eda Benavides Chacón, Maria Stella Uribe Enciso   +1 more
openalex   +1 more source

IMPACT OF INSTITUTIONAL SUPPORT FOR FINANCING SMALL AND MEDIUM-SIZED FARMS UNDER THE NEW CAP 2023-2027

Yordan Kostadinov Georgiev
openalex   +1 more source