Results 171 to 180 of about 3,741,726 (317)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Logic specification for ACIP recommendations [PDF]
Currently, Health Information Systems (HIS) \u2013 which can include Health Information Exchanges (HIEs), IIS and Electronic Health Records (EHRs) \u2013 provide healthcare providers with immunization evaluation and forecasting tools designed to ...
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Comparison of the liver support systems OPAL and ALBUNIQUE in critically ill patients with liver dysfunction. [PDF]
Int J Artif OrgansKrause A +4 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Artificial intelligence agents as advanced decision support systems in public decision-making: evidence from Peru. [PDF]
Front Artif IntellMedrano-Sánchez EJ, Jara J.
europepmc +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
THE ROLE OF COLLABORATIVE SOFTWARE AND DECISION SUPPORT SYSTEMS IN THE SMARTER CITIES [PDF]
The transition from the traditional city to the smart city is made by supported efforts regarding the achievement of a more steady, more efficient, more responsible city, through convergent strategies that deal with Smart Transportation Systems, Energy ...
Virgil Chichernea
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Asthma clinical decision support systems in primary care: an updated scoping review of implementation. [PDF]
NPJ Prim Care Respir MedTibble H, Lee B, Skene I.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Organizing adaptation using agents in serious games
, 2011 Computer games are frustrating if they are too difficult, but boring if they are too easy. This thesis proposes a framework computer games that adjust to the skill level of the user on the fly.
Westra, J. +3 more
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