Results 71 to 80 of about 1,138,079 (262)

The Relationship between emotion regulation strategies and obsessive-compulsive disorder: An experimental study

open access: yesKlinik Psikoloji Dergisi
Due to the limited number of studies in the literature conducted to examine the relationship be-tween emotion regulation strategies and the obsessive-compulsive disorder symptoms, the current study aimed at examining the role of emotion regulation ...
Tuğba Çapar Taşkesen, Mujgan Inozu
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

De la persistance de la dot dans certains pays africains nonobstant sa suppression de leurs législations [PDF]

open access: yesMouvements et Enjeux Sociaux
Après un examen attentif des codes des personnes et de la famille de certains pays africains, il en ressort que les législateurs de ces Etats adoptent, pour contrer sa dénaturation, deux positions opposées.
Patrice POMBO KAPIKANYA
doaj  

Hostility, Harassment, and Violence: On the Limits of ‘Free Speech’ for Minority Feminist Scholars

open access: yesAtlantis, 2020
Following the rich tradition of Indigenous and Black feminists and authors, this article makes use of storytelling to explore the limits of freedom of speech in the academy for feminist scholars belonging to socially marginalized groups and ...
Robyn Bourgeois
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Study of Power Frequency Overvoltage Suppression on UHV Transmission Line

open access: yesKongzhi Yu Xinxi Jishu, 2014
It mainly studied the improvement measures of overvoltage level for UHV transmission line from Jindongnan to Jingmen. It analyzed single-phase grounding load shedding overvoltage and fault-free load shedding overvoltage in the case of the single ...
HAN Mengmeng   +3 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Patterns and Predictors of Tic Suppressibility in Youth With Tic Disorders

open access: yesFrontiers in Psychiatry, 2018
Tic suppression is the primary target of tic disorder treatment, but factors that influence voluntary tic inhibition are not well understood. Several studies using the Tic Suppression Task have demonstrated significant inter-individual variability in tic
Christine A. Conelea   +9 more
doaj   +1 more source

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