Results 51 to 60 of about 7,865 (188)

On Binary structure of Supra Topological space

Boletim da Sociedade Paranaense de Matemática, 2017
In this paper we introduce the new concept of binary supra topology and dealswith concrete examples. Also we examine some binary supra topological properties.Further characterizations and properties of weak and strong forms binary supracontinuity have been obtained.
Lellis Thivagar, Kavitha Jagadeesan
openaire   +4 more sources

Annealing‐Induced Plasticity and Strengthening in Metallic Glasses

Advanced Science, EarlyView.
This work challenges the dogma that annealing inevitably embrittles metallic glasses. We demonstrate that sub‐Tg annealing, guided by positive mixing enthalpy and constrained kinetics, can drive a self‐organized compositional fluctuation that creates an interface‐free heterogeneous structure.
Yingjie Zhang, Jinyue Wang, Leqing Liu, Yuan Wu, Yi‐huan Cao, Jiqi Yu, Zhen Tian, Zhichao Lu, Fengshou Li, Qiang Chen, Guosheng Zhang, Laiquan Shen, Yong Yu, Hui Wang, Suihe Jiang, Xiaobin Zhang, Xiongjun Liu, Zhaoping Lu   +17 more
wiley   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Mesoscopic analysis of networks: applications to exploratory analysis and data clustering

, 2011
We investigate the adaptation and performance of modularity-based algorithms, designed in the scope of complex networks, to analyze the mesoscopic structure of correlation matrices.
Arenas, Alex, Gomez, Sergio, Granell, Clara   +2 more
core   +1 more source

Cellulose Fiber‐Engineered Gradient Interfacial Channels as Ion‐Highways for High‐Loading, Long‐Life Lithium‐Ion Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study presents a papermaking‐inspired strategy to fabricate high‐loading battery electrodes by integrating a cellulose fiber network. This scaffold creates a gradient porous architecture, enabling ultra‐fast electrolyte infiltration and ion transport.
Wenhao Jia, Haiwei Wu, Ruihua Li, Yuting Wang, Zhixiong Zhang, Hanbin Liu, Zhijian Li, Chuanyin Xiong, Yonghao Ni, Qiang Zhang, Li Wang, Xiangming He   +11 more
wiley   +1 more source

Robustness Assessment of Public Transport Networks in Various Graph Representations: Systematic Review, Decision Support, and Case Study

Networks, EarlyView.
ABSTRACT The analysis of certain properties of the underlying graph of a public transport network generates insights about the network's structure. Hereby, the choice of the graph representation depends on a trade‐off between complexity reduction and information preservation to adequately model a public transport network.
Michael Palk, Stefan Voß, Raka Jovanovic   +2 more
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Unlocking the potential of stimuli‐responsive liquid crystal polymer bio‐interfaces for adaptive cell modulation

Responsive Materials, EarlyView.
This Perspective discusses the potential of stimuli‐responsive liquid crystal polymer bio‐interfaces in modulating cell behavior as next generation dynamic artificial scaffolds. Unlike current artificial biomaterials that have static properties, LCPs offer fast, reversible, and spatially programmable deformation that reflects the dynamic properties of ...
Ruth M. C. Verbroekken, Burcu Gumuscu, Albert P. H. J. Schenning   +2 more
wiley   +1 more source

Energy required to pinch a DNA plectoneme [PDF]

, 2018
DNA supercoiling plays an important role on a biological point of view. One of its consequences at the supra-molecular level is the formation of DNA superhelices named plectonemes.
Barde, Céline, Destainville, Nicolas, Manghi, Manoel   +2 more
core   +5 more sources

Hindlimb functional morphology and locomotor biomechanics of the small Late Triassic pseudosuchian reptile Gracilisuchus stipanicicorum (Archosauria: Gracilisuchidae)

Journal of Anatomy, EarlyView.
A three‐dimensional biomechanical model of the musculoskeletal system is used to analyse the potential locomotor functions of the small (~1 kg) Late Triassic archosaurian reptile Gracilisuchus stipanicicorum. The study finds that, potentially like the ancestral archosaur, this taxon was probably quadrupedal, plantigrade and neither strongly sprawling ...
Agustina Lecuona, Emily Keeble, Yuting Lin, John R. Hutchinson   +3 more
wiley   +1 more source