Results 191 to 200 of about 986,627 (254)

Receptor‐Triggered Peptide Self‐Assembly Enables Multivalent Recruitment of Endogenous Antibodies for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Receptor‐triggered supramolecular self‐assembly converts monovalent antibody‐recruiting molecules into multivalent platforms directly on cancer cell membranes. The resulting fibrillar assemblies present clustered haptens that efficiently recruit endogenous antibodies, enabling selective complement‐mediated immune killing of EGFR‐positive cancer cells ...
Yihui Wang   +6 more
wiley   +1 more source

Supramolecular Polymer Additives as Repairable Reinforcements for Dynamic Covalent Networks. [PDF]

open access: yesAdv Mater
van der Tol JJB   +6 more
europepmc   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

open access: yesAdvanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu   +5 more
wiley   +1 more source

Porphyrin‐Based Porous Materials for Antibacterial Applications

open access: yesAdvanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang   +4 more
wiley   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

open access: yesAdvanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang   +12 more
wiley   +1 more source

A hierarchical, compact and efficient phenanthrene supramolecular polymer light harvesting antenna.

open access: yesJ Mater Chem C Mater
Brisse R   +5 more
europepmc   +1 more source

Supramolecular--Polymer Composite Hydrogels: From In Situ Network Observation to Functional Properties

open access: yes
Living cells and organisms are composed of numerous biomolecules and control their concentrations and spatial distribution in a spatiotemporal manner to exhibit intricate biological functions. Inspired by the extracellular matrix, synthetic multi-network
窪田, 亮, Kubota, Ryou
core  

Molecular Rectification: Mechanisms, Modulation Strategies, and Device Realization

open access: yesAdvanced Science, EarlyView.
This review focuses on molecular rectification, from its fundamental mechanisms and modulation strategies to device realization. It summarizes the theoretical framework, modulation strategies, fabrication techniques, characterization methods, and modeling and simulation of molecular rectifiers, while discussing challenges and future directions for ...
Junnan Guo   +8 more
wiley   +1 more source

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