Results 161 to 170 of about 547,344 (286)

Self‐Healing UPy‐Functionalized Polyethylene Networks: A Robust Platform for Resilient and High‐Performance Lithium Battery Separators

open access: yesAdvanced Science, EarlyView.
Self‐healing separators are developed by grafting ureidopyrimidinone (UPy) quadruple hydrogen‐bonding motifs onto PE‐HEMA copolymers, blended with high‐MW PEO via solvent‐free hot‐pressing. The dynamic UPy network enables autonomous healing, restoring functionality after short circuits.
Daniele Callegari   +4 more
wiley   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

open access: yesAdvanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan   +7 more
wiley   +1 more source

Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions

open access: yesAdvanced Science, EarlyView.
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu   +12 more
wiley   +1 more source

Author Correction: Mapping in situ the assembly and dynamics in aqueous supramolecular polymers. [PDF]

open access: yesNat Commun
Du H   +8 more
europepmc   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

open access: yesAdvanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu   +10 more
wiley   +1 more source

Bioelectrochemically Powered Out‐of‐Equilibrium Hydrogels Enable Feedback‐Regulated Functions

open access: yesAdvanced Science, EarlyView.
A bioelectrochemically powered hydrogel operates far from equilibrium via an antagonistic redox cycle that regulates disulfide exchange within a polyrotaxane network. Coupling electrochemical mediator cycling with enzymatic feedback enables dynamic control of hydrogel mechanics and transport properties, driving glucose‐responsive insulin release with ...
Roberto Baretta, Marco Frasconi
wiley   +1 more source

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