Results 91 to 100 of about 3,671 (216)
European Journal of Organic Chemistry, Volume 29, Issue 5, 7 February 2026.This study exploits the comparable binding tolerances between the fluorinase enzyme and the A2A adenosine receptor towards the development of novel C‐2 functionalised 5′‐fluorodeoxy‐adenosine (FDA)‐based agonists with enzymatic 18F‐labelling capability for positron emission tomography (PET).
Nicolas Charalambous +6 more
wiley +1 more source
CrystalsIrbesartan (IRB) is a commonly used BCS Class II antihypertensive drug requiring dissolving capacity enhancement to address oral bioavailability limitations.
Junxiao Wang +6 more
doaj +1 more source
IUCrJ, 2018 The single-crystal X-ray structure of a 6-component organic-salt alloy (hexanary) of naftopidil (1) (an active pharmaceutical ingredient) with benzoic acid (2) and four different hydroxy-substituted benzoic acids, i.e.
Rambabu Dandela +3 more
doaj +1 more source
Stimuli‐Responsive Afterglow from Luminescent Liquid Crystal Elastomers
Advanced Materials, Volume 38, Issue 7, 2 February 2026.An active glow luminescent system for encoding, signaling, and tracking in dark environments has been developed by integrating inorganic ultralong afterglow phosphors with adaptive liquid crystal elastomer actuators. Abstract Stimuli‐responsive luminescent polymeric materials which combine afterglow emission with mechanical flexibility and adaptability
Lansong Yue +2 more
wiley +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2020 The crystal and molecular structures of the title 1:2 co-crystal, C14H14N4O2·2C7H6O2, are described. The oxalamide molecule has a (+)-antiperiplanar conformation with the 4-pyridyl residues lying to either side of the central, almost planar C2N2O2 ...
Sang Loon Tan, Edward R. T. Tiekink
doaj +1 more source
Investigation of an amide-pseudo amide hydrogen bonding motif within a series of theophylline:amide cocrystals [PDF]
, 2016 The pharmaceutically active compound theophylline (T) was cocrystallised with the amides formamide (1), acetamide (2), N-methylformamide (3), N,N-dimethylformamide (4), benzamide (5) and pyrazinamide (6), with systems T:1, T:5 and T:6 displaying ...
Davis R. E. +6 more
core +3 more sources
Advanced Optical Materials, Volume 14, Issue 7, 16 February 2026.Intramolecular bridge‐locking frustrates detrimental anti‐parallel packing in evaporated organic films. This design enhances net polar orientation, leading to a twofold off‐resonance increase in the second‐order nonlinear susceptibility (χ(2)) without electric‐field poling.
Pierre‐Luc Thériault +6 more
wiley +1 more source
IUCrJ, 2016 A novel design strategy for cocrystals of a sulfonamide drug with pyridine carboxamides and cyclic amides is developed based on synthon identification as well as size and shape match of coformers.
Geetha Bolla, Ashwini Nangia
doaj +1 more source
Site selectivity of halogen oxygen bonding in 5- and 6-haloderivatives of uracil [PDF]
, 2019 Seven 5-and 6-halogenated derivatives of uracil or 1-methyluracil (halogen = Cl, Br, I) were studied by single crystal X-ray diffraction. In contrast with pure 5-halouracils, where the presence of N-H…O and C-H…O hydrogen bonds prevents the formation ...
Portalone, Gustavo
core +1 more source
ChemistryEurope, Volume 4, Issue 2, February 2026.This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego +4 more
wiley +1 more source