Site selectivity of halogen oxygen bonding in 5- and 6-haloderivatives of uracil [PDF]
, 2019 Seven 5-and 6-halogenated derivatives of uracil or 1-methyluracil (halogen = Cl, Br, I) were studied by single crystal X-ray diffraction. In contrast with pure 5-halouracils, where the presence of N-H…O and C-H…O hydrogen bonds prevents the formation ...
Portalone, Gustavo
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Investigation of an amide-pseudo amide hydrogen bonding motif within a series of theophylline:amide cocrystals [PDF]
, 2016 The pharmaceutically active compound theophylline (T) was cocrystallised with the amides formamide (1), acetamide (2), N-methylformamide (3), N,N-dimethylformamide (4), benzamide (5) and pyrazinamide (6), with systems T:1, T:5 and T:6 displaying ...
Davis R. E. +6 more
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Ethyl 3,4-bis(acetyloxy)-2-(4-methoxyphenyl)pyrrolidine-1-carboxylate
IUCrData, 2020 The title pyrrolidine compound, C18H23NO7, is a tetra-substituted species in which the five-membered ring has a twisted conformation with the twist occurring in the C—C bond bearing the adjacent acetyloxy substituents; the Cm—Ca—Ca—Cp torsion angle is ...
Sofia Dallasta Pedroso +7 more
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Creation of a ternary complex between a crown ether, 4-aminobenzoic acid and 3,5-dinitrobenzoic acid [PDF]
, 2013 YesThe creation of ternary multi-component crystals through the introduction of 18-crown-6 to direct the hydrogen-bonding motifs of the other molecular components was investigated for 3,5-dinitrobenzoic acid (3,5-dnba) with 4-aminobenzoic acid (4-aba ...
Boardman, N.D. +3 more
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Acta Crystallographica Section E, 2012 The title compound, C23H17N3O, has been previously described in a monoclinic P21/c polymorph with Z = 4 [Asiri, Al-Youbi, Faidallah, Ng & Tiekink (2011). Acta Cryst. E67, o2449].
Abdullah M. Asiri +4 more
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Altering physical properties of pharmaceutical co-crystals in a systematic manner [PDF]
, 2014 Systematic structure-property studies on a series of co-crystals of potential cancer drugs with aliphatic dicarboxylic acids were undertaken. This study reveals that systematic changes to the molecular nature of the co-crystallizing agent combined with ...
Aakeröy, Christer B. +2 more
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2-(2,5-Dichlorobenzenesulfonamido)-3-methylbutanoic acid
Acta Crystallographica Section E, 2010 The structure of the title compound, C11H13Cl2NO4S, shows one sulfonamide-O atom to lie almost in the plane of the benzene ring [C—C—S—O = −178.7 (2) °] and the other to one side [C—C ...
Islam Ullah Khan +4 more
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Assembly with Multinuclear Silver-Ethynediide/-Ethynide Supramolecular Synthons [PDF]
Acta Crystallographica Section A Foundations and Advances, 2014 Over the past 15 years, our group has conducted a systematic investigation on the synthesis and structural characterization of a series of silver(I) double and multiple salts containing silver carbide Ag2C2n (n = 1, 2), in which the all-carbon dianion ethynediide C22-is generally capsulated inside a polyhedral Agm (m = 6-10) cage, whereas C42-exhibits ...
openaire +1 more source
Green synthesis and biological evaluation of novel 5-fluorouracil derivatives as potent anticancer agents [PDF]
, 2019 This study reports the formation of 5-FU co-crystals with four different pharmacologically safe co-formers; Urea, Thiourea, Acetanilide and Aspirin using methanol as a solvent. Two fabrication schemes were followed i.e., solid-state grinding protocol, in
Abdelghani +53 more
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Structural characterization of new fluorinated mesogens obtained through halogen-bond driven self-assembly [PDF]
, 2017 We describe the synthesis and characterization of new trimeric complexes obtained upon halogen-bond driven self-assembly of 1,4-diiodotetrafluorobenzene or α,ω- diiodoperfluoroalkanes, acting as XB-donors, with an alkoxystilbazole derivative ...
Cavallo, Gabriella +7 more
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