Results 51 to 60 of about 3,703 (215)

5-Hydroxy-7-phenyl-5-(prop-2-yn-1-yl)-5,6-dihydro-1-benzofuran-2(4H)-one monohydrate

Acta Crystallographica Section E, 2010
In the title compound, C17H14O3·H2O, the six-membered ring, which adopts a half-chair conformation, makes a dihedral angle of 24.3 (2)° with the phenyl ring.
Laura Torre-Fernández, Marcos G. Suero, Santiago García-Granda   +2 more
doaj   +1 more source

Halogen and hydrogen bonding in multicomponent crystals of tetrabromo-1H-benzotriazole [PDF]

, 2017
4,5,6,7-Tetrabromo-1H-benzotriazole (TBBT) is still considered a reference inhibitor of casein kinase II (CK2), a valuable target for anticancer therapy, even though the poor solubility in water of this active pharmaceutical ingredient (API) has ...
Baldrighi, Michele, Metrangolo, Pierangelo, Pilati, Tullio, Resnati, Giuseppe, Terraneo, Giancarlo   +4 more
core   +2 more sources

Quaternary and quinary molecular solids based on structural inequivalence and combinatorial approaches: 2-nitroresorcinol and 4,6-dichlororesorcinol

IUCrJ, 2021
A synthetic strategy for the formation of stoichiometric quaternary and nonstoichiometric quinary solids is outlined. A series of 2-nitroresorcinol-based quaternary cocrystals were developed from binary precursors in two conceptual stages.
Madhu Rajkumar, Gautam R. Desiraju
doaj   +1 more source

Connectivity and topology invariance in self-assembled and halogen-bonded anionic (6,3)-networks [PDF]

, 2018
open5noWe report here that the halogen bond driven self-assembly of 1,3,5-trifluorotriiodobenzene with tetraethylammonium and -phosphonium bromides affords 1:1 co-crystals, wherein the mutual induced fit of the triiodobenzene derivative and the bromide ...

core   +1 more source

Co-crystal structures of furosemide:urea and carbamazepine:indomethacin determined from powder x-ray diffraction data [PDF]

, 2020
Co-crystallization is a promising approach to improving both the solubility and the dissolution rate of active pharmaceutical ingredients. Crystal structure determination from powder diffraction data plays an important role in determining co-crystal ...
Al Rahal, Okba, Majumder, Mridul, Shankland, Kenneth, Spillman, Mark J., van de Streek, Jacco   +4 more
core   +2 more sources

Chiral gels derived from secondary ammonium salts of (1R,3S)-(+)-camphoric acid

Beilstein Journal of Organic Chemistry, 2010
In order to have access to chiral gels, a series of salts derived from (1R,3S)-(+)-camphoric acid and various secondary amines were prepared based on supramolecular synthon rationale.
Tapas Kumar Adalder, N. N. Adarsh, Ravish Sankolli, Parthasarathi Dastidar   +3 more
doaj   +1 more source

Highly fluorinated naphthalenes and bifurcated C–H⋯F–C hydrogen bonding [PDF]

, 2014
The synthesis and crystal structures of 1,2,4,5,6,8-hexafluoronaphthalene and 1,2,4,6,8-pentafluoronaphthalene are reported. Intermolecular interactions are dominated by offset stacking and by C–H⋯F–C hydrogen bonds.
Allen, Allen, Alvarez, Amii, Anthony J. H. M. Meijer, Bagryanskaya, Becke, Berman, Berman, Blessing, Bondi, Brammer, Brammer, Brammer, Brammer, Chanh, Clot, Coates, Cozzi, Desiraju, Dolomanov, Donohue, Dunitz, Dunitz, Etter, Frisch, Frisch, Jason R. Loader, Kroon, Laev, Lee Brammer, Lommerse, Macrae, Macrae, Mareque Rivas, McLean, Meresse, Meresse, Raghavachari, Reichenbächer, Robin N. Perutz, Rowland, Schwalbe, Sheldrick, Sheldrick, Sheldrick, Stefano Libri, Steiner, Steiner, Steiner, Sutor, Sutor, Taylor, Thalladi, Thomas, Wood   +55 more
core   +1 more source

One‐Pot Ruthenium‐Catalyzed Synthesis of Benzyl/Allyl‐Halide Substituted (dihydro)naphthalenes via Radical Benzannulation

ChemistryEurope, EarlyView.
A one‐pot protocol to synthesize reactive benzyl‐ and allyl‐halide‐substituted (dihydro)naphthalenes from 2,3‐aryl‐1,3‐butadiene substrates and halogenated alkanes has been developed, using [Cp*RuCl(PPh3)2] as the catalyst. Mechanistic studies revealed an atom transfer radical addition and radical benzannulation sequence, followed by HCl elimination ...
Nicole S. van Leeuwen, David Vesseur, Thijmen Bonhoff, Jeffrey van Laar, Coert E. J. van Lare, Simon Mathew, Sonja Pullen, Joost N. H. Reek, Aalbert Zwijnenburg, Bas de Bruin   +9 more
wiley   +1 more source

Self-assembly in solution of a reversible comb-shaped supramolecular polymer [PDF]

, 2010
We report a single step synthesis of a polyisobutene with a bis-urea moiety in the middle of the chain. In low polarity solvents, this polymer self-assembles by hydrogen bonding to form a combshaped polymer with a central hydrogen bonded backbone and ...
Abed S., Arnaud A., Bellot M., Berl V., Bernard J., Binder W. H., Binder W. H., Binder W. H., Binder W. H., Binder W. H., Boileau S., Bouteiller L., Bouteiller L., Brunsveld L., Casassa E. F., Ciferri A., Colombani O., Colombani O., Cordier P., Ducouret G., Ercolani G., Fang Z., Hammond M. R., Huang F., Ikkala O., Isare B., Isare B., Kato T., Kato T., Kato T., Knoben W., Knoben W., Lange R. F. M., Lortie F., Miyawaki A., Mueller M., Ohkawa H., Pinault T., Rosselli S., Ruokolainen J., Scherman O. A., Schirle M., Shikata T., Simic V., ten Brinke G., ten Cate A. T., Todd E. M., van der Gucht J., Vonau F., Yamaguchi N., Yount W. C.   +50 more
core   +4 more sources

Next Generation Hosts for Protein Recognition, Assembly and More

Chemistry – A European Journal, EarlyView.
The original design of synthetic receptors for proteins was based on macrocycles with a hydrophobic core and a polar/charged periphery. This design, geared towards protein recognition, facilitates receptor self‐assembly. Macrocycle oligomerization, in turn, contributes to protein assembly as evidenced in many cocrystal structures.
Peter B. Crowley
wiley   +1 more source