Results 51 to 60 of about 3,671 (216)
Halogen and hydrogen bonding in multicomponent crystals of tetrabromo-1H-benzotriazole [PDF]
, 2017 4,5,6,7-Tetrabromo-1H-benzotriazole (TBBT) is still considered a reference inhibitor of casein kinase II (CK2), a valuable target for anticancer therapy, even though the poor solubility in water of this active pharmaceutical ingredient (API) has ...
Baldrighi, Michele +4 more
core +2 more sources
Co-crystal structures of furosemide:urea and carbamazepine:indomethacin determined from powder x-ray diffraction data [PDF]
, 2020 Co-crystallization is a promising approach to improving both the solubility and the dissolution rate of active pharmaceutical ingredients. Crystal structure determination from powder diffraction data plays an important role in determining co-crystal ...
Al Rahal, Okba +4 more
core +2 more sources
Self-assembly of cis- and trans-cyclic-1,2-diols. Supramolecular synthon equivalence between cis-1,2-diols and primary amides [PDF]
, 2005 Inspite of the fact that the self-assembly of compounds containing hydroxyl group has been enormously documented in the literature, our studies with aliphatic cyclic diols have offered the unique opportunity to examine the self-assembly of gauche and ...
Begum, N.S. +3 more
core +1 more source
IUCrJ, 2021 A synthetic strategy for the formation of stoichiometric quaternary and nonstoichiometric quinary solids is outlined. A series of 2-nitroresorcinol-based quaternary cocrystals were developed from binary precursors in two conceptual stages.
Madhu Rajkumar, Gautam R. Desiraju
doaj +1 more source
Is there any point in making co-crystals? [PDF]
, 2015 Citation: Aakeroy, C. (2015). Is there any point in making co-crystals? Acta Crystallographica Section B-Structural Science Crystal Engineering and Materials, 71, 387-391.
Aakeröy, Christer B.
core +1 more source
Chiral gels derived from secondary ammonium salts of (1R,3S)-(+)-camphoric acid
Beilstein Journal of Organic Chemistry, 2010 In order to have access to chiral gels, a series of salts derived from (1R,3S)-(+)-camphoric acid and various secondary amines were prepared based on supramolecular synthon rationale.
Tapas Kumar Adalder +3 more
doaj +1 more source
Connectivity and topology invariance in self-assembled and halogen-bonded anionic (6,3)-networks [PDF]
, 2018 open5noWe report here that the halogen bond driven self-assembly of 1,3,5-trifluorotriiodobenzene with tetraethylammonium and -phosphonium bromides affords 1:1 co-crystals, wherein the mutual induced fit of the triiodobenzene derivative and the bromide ...
core +1 more source
Control Strategies in Guanine Biocrystallization
Angewandte Chemie International Edition, EarlyView.Biological guanine crystals produce spectacular photonic phenomena in animals and hold great promise as new, sustainable optical materials. We review how organisms precisely control the structure, morphologies, and resulting optical properties of these crystals using a set of ingenious ‘design’ strategies, including control of pH, template‐directed ...
Shashanka S. Indri +2 more
wiley +1 more source
ChemistryEurope, EarlyView.A one‐pot protocol to synthesize reactive benzyl‐ and allyl‐halide‐substituted (dihydro)naphthalenes from 2,3‐aryl‐1,3‐butadiene substrates and halogenated alkanes has been developed, using [Cp*RuCl(PPh3)2] as the catalyst. Mechanistic studies revealed an atom transfer radical addition and radical benzannulation sequence, followed by HCl elimination ...
Nicole S. van Leeuwen +9 more
wiley +1 more source
Highly fluorinated naphthalenes and bifurcated C–H⋯F–C hydrogen bonding [PDF]
, 2014 The synthesis and crystal structures of 1,2,4,5,6,8-hexafluoronaphthalene and 1,2,4,6,8-pentafluoronaphthalene are reported. Intermolecular interactions are dominated by offset stacking and by C–H⋯F–C hydrogen bonds.
Allen +55 more
core +1 more source