Results 61 to 70 of about 106,351 (226)

Crystal design approaches for the synthesis of paracetamol co-crystals [PDF]

, 2012
Crystal engineering principles were used to design three new co-crystals of paracetamol. A variety of potential cocrystal formers were initially identified from a search of the Cambridge Structural Database for molecules with complementary hydrogen-bond ...
Kraft, A., Powell, Anthony V., Srirambhatla, V. K., Watt, S.   +3 more
core   +1 more source

Supramolecular synthons in hydrates and solvates of lamotrigine: a tool for cocrystal design

Acta Crystallographica. Section B: Structural Science, Crystal Engineering and Materials
Robustness of supramolecular synthons in the lamotrigine solvates and hydrate has been investigated in order to be applied for the lamotrigine cocrystals design.
G. Pavlović, E. Lekšić, Ernest Meštrović   +2 more
semanticscholar   +1 more source

Using crystallography, topology and graph set analysis for the description of the hydrogen bond network of triamterene: a rational approach to solid form selection

Chemistry Central Journal, 2017
This study has demonstrated the use of crystallography, topology and graph set analysis in the description and classification of the complex hydrogen bonded network of triamterene.
David S. Hughes, Amit Delori, Abida Rehman, William Jones   +3 more
doaj   +1 more source

Two Crystal Forms of 4′-Methyl-2,4-dinitrodiphenylamine: Polymorphism Governed by Conformational Flexibility of a Supramolecular Synthon

Crystals, 2023
Single crystals of two polymorphic forms of 4′-methyl-2,4-dinitrodiphenylamine were obtained by crystallization and characterized by X-ray diffraction analysis.
Ivan V. Fedyanin, Aida I. Samigullina
doaj   +1 more source

Next Generation Hosts for Protein Recognition, Assembly and More

Chemistry – A European Journal, EarlyView.
The original design of synthetic receptors for proteins was based on macrocycles with a hydrophobic core and a polar/charged periphery. This design, geared towards protein recognition, facilitates receptor self‐assembly. Macrocycle oligomerization, in turn, contributes to protein assembly as evidenced in many cocrystal structures.
Peter B. Crowley
wiley   +1 more source

[O-Isopropyl-N-(4-nitrophenyl)thiocarbamato-κS]-(tri-4-tolylphosphine-κP)gold(I) [PDF]

, 2018
The synthesis, spectroscopic characterization and X-ray crystal structure of the title compound, (4-tolyl)3PAu[SC(O-i-Pr)=NC6H4NO2-4] (1) are described. Spectroscopy exhibited the expected features confirming the formation of the compound.
Tiekink, Edward R. T. *, Yeo, Chien Ing *   +1 more
core   +1 more source

Dual‐State Photophysical Modulation via Bifurcated Hydrogen Bonding in a U‐Shaped Dipyridophenazine‐Cored Donor‐π‐Acceptor‐π‐Donor Fluorophore

Chemistry – A European Journal, EarlyView.
A donor–π–acceptor–π–donor (D–π–A–π–D) fluorophore bearing a U‐shaped dipyridophenazine core forms bifurcated hydrogen bonds with neutral donors such as sulfonamides or water. This interaction modulates both ground and excited states, enabling red‐shifted emission and enhanced photoluminescence in solution and solid state.
Kimiya Takei, Shunsuke Kobashi, Divya, Norimitsu Tohnai, Satoshi Minakata, Yoichi Kobayashi, Piotr de Silva, Youhei Takeda   +7 more
wiley   +1 more source

Green synthesis and biological evaluation of novel 5-fluorouracil derivatives as potent anticancer agents [PDF]

, 2019
This study reports the formation of 5-FU co-crystals with four different pharmacologically safe co-formers; Urea, Thiourea, Acetanilide and Aspirin using methanol as a solvent. Two fabrication schemes were followed i.e., solid-state grinding protocol, in
Abdelghani, Ahmed, Aisha Liaqat, Ansari, Baumgartner, Carrillo, Dai, Delori, Dong, Douroumis, Fang, Fang, Farhat Jubeen, Farooq Sher, Imran Sajid, Jubeen, Karimi-Jafari, Köksal Karayildirim, Langley, Li, Li, Likhitha, Misbah Sultan, Miura, Mohana, Moisescu-Goia, Moku, Nadzri, Ofonime Udofot, Patel, Petaccia, Qin, Qin, Qin, Radwan, Rakesh, Rakesh, Reinsch, Sania Zafar Iqbal, Shakeel, Sonawane, Stoler, Subudhi, Suthindhiran, Vichai, Wang, Yan, Zha, Zha, Zhang, Zhang, Zhao, Zhao, Zhou   +53 more
core   +2 more sources

Building a Cocrystal by Using Supramolecular Synthons for Pressure-Accelerated Heteromolecular Azide-Alkyne Cycloaddition.

Chemistry, 2019
Facilitated by the supramolecular synthons of carboxylic acids and amides through cooperative hydrogen-bonding and arene-perfluoroarene interactions, the azide-alkyne cycloaddition reaction between two different molecules in a cocrystal was achieved ...
Xiao Meng, Changqing Chen, Xinyuan Deng, Zhangyuan Wang, Qi Chen, Yuguo Ma   +5 more
semanticscholar   +1 more source

Synthesis and Crystal Structure of Ethyl 5-(4-Bromophenyl)-7-methyl-3-oxo-2,3-dihidro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate

Molbank, 2023
Thiazolopyrimidines are attractive to medical chemists as new antitumor agents due to their high inhibitory activity against the replication process of tumor cells and the easy modification of their structure by changing the number and nature of ...
Artem Agarkov, Anna Nefedova, Alexander Ovsyannikov, Igor Litvinov, Svetlana Solovieva, Igor Antipin   +5 more
doaj   +1 more source