Results 121 to 130 of about 15,560 (165)
Atypical Frontotemporal Dementia Associated With SQSTM1 Gene Mutation: A Clinicopathological Case
Neuropathology, Volume 45, Issue 6, December 2025.ABSTRACT A 78‐year‐old man presented with a six‐year history of progressive memory decline, initially manifesting as recent memory impairment and mild anomia, which gradually evolved into motor clumsiness, gait disturbances, language difficulties, behavioral changes, and late‐onset parkinsonism. He had been diagnosed with Paget disease of bone (PDB) at
Christian Espinoza‐Vinces +8 more
wiley +1 more source
Neuronal network disintegration: common pathways linking neurodegenerative diseases [PDF]
, 2016 Neurodegeneration refers to a heterogeneous group of brain disorders that progressively evolve. It has been increasingly appreciated that many neurodegenerative conditions overlap at multiple levels and therefore traditional clinicopathological ...
Ahmed, RM +10 more
core +2 more sources
Cancer, Volume 131, Issue 21, 1 November 2025.Proteolysis‐targeting chimeras use the ubiquitin (Ub)–proteasome system to selectively break down oncogenic proteins, including previously undruggable targets. By providing long‐lasting suppression with lower toxicity, they are becoming a revolutionary approach for personalized cancer treatment.
Yamile Abuchard Anaya +7 more
wiley +1 more source
Longitudinal assessment of reflexive and volitional saccades in Niemann-Pick Type C disease during treatment with miglustat [PDF]
, 2015 Peer reviewedPublisher ...
Abel, Larry A +4 more
core +3 more sources
Complement dysregulation in human tauopathies
Brain Pathology, Volume 35, Issue 6, November 2025.Complement protein and activation product levels were assessed in post‐mortem frontal cortex from three distinct subtypes of Tauopathy: Corticobasal degeneration, globular glial tauopathy, and Pick's disease. Quantification of complement proteins by immunohistochemistry and ELISA showed elevation of key complement proteins (C1q) regulators (FI) and ...
Jacqui Nimmo +3 more
wiley +1 more source
Imaging tau pathology in Parkinsonisms
npj Parkinson's Disease, 2017 The recent development of positron emission tomography radiotracers targeting pathological tau in vivo has led to numerous human trials. While investigations have primarily focused on the most common tauopathy, Alzheimer’s disease, it is imperative that ...
Sarah Coakeley, Antonio P. Strafella
doaj +1 more source
European Journal of Neurology, Volume 32, Issue 11, November 2025.Objective: Heart rate variability (HRV) is a promising tool for autonomic dysfunction assessment, especially Deceleration capacity (DC), a sensitive parasympathetic marker. M&M: Study in patients with isolated REM sleep behavior disorder, Parkinson's disease, multiple system atrophy, and supranuclear palsy as compared to healthy control subjects ...
Elisabeth Ruppert +9 more
wiley +1 more source
Angewandte Chemie International Edition, Volume 64, Issue 41, October 6, 2025.Synthetic neuromelanin analogs are used to characterize iron and copper binding to the melanin moiety or to conjugated protein (β‐lactoglobulin). The models confirm the presence of paramagnetic mononuclear‐binding sites and iron or mixed‐metal clusters that enhance water proton relaxation to varying degrees.
Niklas Wallstein +11 more
wiley +1 more source
Diplopia and eye movement disorders.
, 2004 Published ...
Danchaivijitr, C, Kennard, C
core +2 more sources
Effects of dance therapy on balance, gait and neuro-psychological performances in patients with Parkinson's disease and postural instability [PDF]
, 2012 Postural Instability (PI) is a core feature of Parkinson’s Disease (PD) and a major cause of falls and disabilities. Impairment of executive functions has been called as an aggravating factor on motor performances. Dance therapy has been shown effective
Agnetti, Virgilio +6 more
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